Anemia frequently complicates chronic kidney disease (CKD). We investigated here the effect of adenine-induced CKD in rats on erythrocyte count (EC), hematocrit (PCV) and hemoglobin (Hb) concentration, as well as on the activity of L-gamma-glutamyl transferase (GGT) and the concentrations of iron (Fe), transferrin (Tf), ferritin (F), total iron binding capacity (TIBC) / unsaturated iron binding...

Introduction: The severity of chronic renal failure (CRF) classified by professional guidelines in five stages, stage 5 is a severe illness often called end kidney or disease (ESRD), dialysis may be used for this stage. Dialysis treatments replace some these functions through diffusion (waste removal) and ultrafiltration (fluid removal). Hemodialysis, process purifying the blood, when kidneys a...

The Access(®) soluble transferrin receptor (sTfR) is considered the world's first automated chemiluminescence immunoassay. In this study, the diagnostic utility of this and other tests for serum iron were evaluated by studying their interrelationships with inflammation. A total of 367 patients with anemia (iron deficiency anemia [IDA], 157; anemia of chronic disease [ACD], 210) and 80 normal co...

Abstract Background and Aims Chronic kidney disease (CKD) is widely linked to chronic inflammation, with a higher incidence in the advanced stages of disease. Recognition systemic inflammation may be useful for prompt diagnosis management various CKD related disorders open door towards development application anti-inflammatory strategy treatments. This case-control cross-sectional study investi...

BACKGROUND Iron disorders are common and complex in chronic kidney disease (CKD). We sought to determine whether a 3-marker index would improve the classification of iron disorders in CKD anaemia. METHODS We studied the association between Hb level and iron indexes combining 2 or 3 of the following markers: serum ferritin (<40 ng/mL), transferrin saturation (TSAT<20%) and total iron binding c...

The major purpose of the present investigation was to study the effects of different concentrations of residual chlorine on serum iron related parameters in rats. Feeding male rats with water containing 80 ppm of residual chlorine daily for 5 days reduced serum levels of ceruloplasmin, copper, iron and hemoglobin by approximately 27%,23%,6% and 4%, respectively. Higher reductions in serum ...

Background: Iron requirements are increased in adolescent girls with growth and the onset of menarche and remain high in women until menopause. Methods: We conducted a study on two study groups of girls in age group 18-25 years belonging to different socioeconomic classes as per the Modified Kuppuswamy’s Scale to study the effect of the phases of menstrual cycle & socioeconomic class on the iro...

UNLABELLED BACKGROUND There had been conflicting reports with levels of markers of iron metabolism in HIV infection. This study was therefore aimed at investigating iron status and its possible mediation of severity of HIV- 1 infection and pathogenesis. METHOD Eighty (80) anti-retroviral naive HIV-1 positive and 50 sero-negative controls were recruited for the study. Concentrations of seru...

It has been anticipated that iron and ferritin burden in patients with beta thalassemia major is associated with enhanced free radical formation and blemished antioxidant defense system. The goal of study was to scrutinize impact of serum iron, total iron binding capacity (TIBC), ferritin and erythrocyte catalase in patients with beta thalassemia major. 140 beta thalassemia major patients were ...