Thyroid hormone has pleiotropic effects on cochlear development, and genomic variation influences the severity of associated hearing deficits. DW/J-Pou1f1dw/dw mutant mice lack pituitary thyrotropin, which causes severe thyroid hormone deficiency and profound hearing impairment. To assess the genetic complexity of protective effects on hypothyroidism-induced hearing impairment, an F1 intercross...

background: more than a billion people have some form of disabilities worldwide. persons living with a disability have many needs (including physically, mentally, and socially needs). estimating the size of disabled population is a challenge in health systems. an innovative indirect method to estimate the size of populations is network scale up (nsu) having widely used for hidden populations. t...

objectives: the prevalence of consanguineous marriage is about 30 % in iran and this can increase the probability of incidence of genetic impairments such as hearing impairments. hearing impairment in comparison with other hereditary disorders is the most incident. the purpose of this survey is to identify the prevalence of consanguinity among the parents of sensoryneural hearing impaired stude...

Deafness is a sensory impairment which results in a partial or total loss in reception of sound. The intensity of sound can be measured in decibels (dB). It is usual to assess hearing thresholds at frequencies of 0.25, 0.5, 1, 2, 4 and 8 KHz. Sounds of each frequency are presented at different intensities to a subject and the response is recorded graphically as an audiogram. A loss in hearing i...

120 cases of iranian soldiers complaining of hearing loss, were studied over a period of three years at the ghaem medical center in mashad,iran. there was adequate information in iii cases that their engagement in different types of explosions had caused their hearing impairment. the following aspects were evaluated: 1- categorization of their hearing impairment. 2- the otoscopic findings. 3- t...