The mainstay of treatment for thrombosis, the formation of occlusive platelet aggregates that often lead to heart attack and stroke, is antiplatelet therapy. Antiplatelet therapy dosing and resistance are poorly understood, leading to potential incorrect and ineffective dosing. Shear rate is also suspected to play a major role in thrombosis, but instrumentation to measure its influence has been...

background: the interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries. objective: to understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from c...

this paper aims at investigating the effects of weld nugget size and expulsion on the mechanical properties of low carbon steel resistance spot welds using tensile-shear test. mechanical performance of spot welds are described in terms of failure mode, peak load and failure energy obtained from the tensile-shear test. the effects of voids and porosity as well as electrode indentation associated...

A complete investigation on the free vibration of bilayer graphene nanoribbons (BLGNRs) mod-eled as sandwich beams taking into account tensile-compressive and shear effects of van der Waals (vdWs) interactions between adjacent graphene nanoribbons (GNRs) as well as between GNRs and polymer matrix is performed in this research. In this modeling, nanoribbon layers play role of sandwich beam layer...

This paper focuses on a hydraulic radius separation approach used to calculate the boundary shear stress in terms of bed and wall shear stress proposed in a trapezoidal channel. The average bed and sidewall shear stress in smooth trapezoidal open channels are derived after using Guo & Julien (2005) early equations taking a part of an investigation to cover both rectangular and trapezoidal chann...

In this article, bending, buckling, and free vibration of viscoelastic sandwich plate with carbon nanotubes reinforced composite facesheets and an isotropic homogeneous core on viscoelastic foundation are presented using a new first order shear deformation theory. According to this theory, the number of unknown’s parameters and governing equations are reduced and also the using of shear correct...

Self-assembled lamellar structures composed of block copolymers are simulated by molecular dynamics. The response of a bulk system to external shear is investigated, in particular, the average energy, the entropy production, and the stability of the lamellae's orientation. We distinguish two orientations, a parallel orientation in which the normal to the lamellae sheets lies in the direction of...

2.02.4.1 Finite-strain Effects in Bulky or Massive Bodies 71 2.02.4.2 Nonlinear Finite-strain Effects in Columns, Plates and Shells Soft in Shear 72 2.02.4.3 Discrepancy between Engesser’s and Haringx’s Formulas: New Paradox and its Resolution 73 2.02.4.4 Shear Stiffness Associated with Second-order Strain 74 2.02.4.5 Differential Equations of Equilibrium Associated with Different Finite-strain...

Gravitational lensing by large-scale structure induces weak coherent alignments in the shapes of background galaxies. Here we present evidence for the detection of this ‘cosmic shear’ at the 3.4σ significance level with the William Herschel Telescope. Analysis and removal of notable systematic effects, such as shear induced by telescope optics and smearing by tracking and seeing, are conducted ...

We study the pinch-off dynamics of droplets of yield stress and shear thinning fluids. To separate the two non-Newtonian effects, we use a yield stress material for which the yield stress can be tuned without changing the shear thinning behavior, and a shear thinning system (without a yield stress) for which the shear thinning can be controlled over a large range, without introducing too much e...