Shotgun wounds can result in devastating functional and aesthetic consequences for patients. There is no consensus in terms of removing or retaining foreign bodies such as shotgun pellets. In this report a 54-year-old man who suffered from accidental shotgun wounds on the face approximately 26 years ago is presented. Although most of pellets were still present, there were no symptoms such as po...

Recent interest in proteomics has been fueled by the completion of multiple genome projects and ignited by the common need of biologists to rapidly and comprehensively evaluate complex samples of proteins on a global level. 'Shotgun proteomics' refers to the direct analysis of complex protein mixtures to rapidly generate a global profile of the protein complement within the mixture. This approa...

33 T he prevailing method of determining the sequence of a long DNA segment is the shotgun sequencing approach, in which a random sampling of short fragment sequences is acquired and then assembled by a computer program to infer the sampled segment's sequence. In the early 1980s, such segments were typically on the order of 5,000 to 10,000 base pairs (5 to 10 kbp). By 1990, this method was sequ...