نتایج جستجو برای: signaling molecules

تعداد نتایج: 471054  

Journal: :مجله علوم اعصاب شفای خاتم 0
zeinab sadat hosseini islamic azad university, mashhad branch, mashhad, iran nikoo saeedi member of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

neurological inflammatory diseases are developing rapidly. different factors involved in the pathogenesis of these diseases. in this article, we discuss some of the mechanisms are dealt with. an aberrant procedure of beta-amyloid precursor protein (bapp) to form neurotoxic beta-amyloid peptides and an accumulated insoluble polymer of beta –amyloid (ba) that forms the senile plaque. the above pr...

Hossein Abde-Ahad, Mahdi Hassanian, Mohammad Jalili-Nik, Safieh Ebrahimi,

Thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. The pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (CAMs) and promoting the secretion of inflammatory chemokines and cytokines. Dysregulated signaling functions of thro...

Journal: :Current Opinion in Endocrine and Metabolic Research 2021

G-protein–coupled receptors (GPCRs) regulate many facets of homeostasis by sensing extracellular signaling molecules. To exert a plethora roles, GPCRs use divergent and intricate networks. better understand the role GPCR signaling, it is an important goal to identify contribution every signal transducer its effectors. Recent advances in methodologies have provided unprecedented opportunity char...

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