نتایج جستجو برای: silencing

تعداد نتایج: 34670  

Journal: :Nature 2012

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Journal: :Cell 2001

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Journal: :Science-Business eXchange 2013

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Journal: :Genome Biology 2002

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Journal: :eLife 2017

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Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Antony M Jose Jessica J Smith Craig P Hunter

Double-stranded RNA (dsRNA) triggers RNA interference (RNAi) to silence genes of matching sequence. In some animals this experimentally induced silencing is transported between cells, and studies in the nematode Caenorhabditis elegans have shown that the dsRNA channel SID-1 is required for the import of such transported silencing signals. Gene silencing can also be triggered by endogenously exp...

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Journal: :Genetics 1998
J S Smith C B Brachmann L Pillus J D Boeke

Transcriptional silencing in Saccharomyces cerevisiae occurs at the silent mating-type loci HML and HMR, at telomeres, and at the ribosomal DNA (rDNA) locus RDN1. Silencing in the rDNA occurs by a novel mechanism that depends on a single Silent Information Regulator (SIR) gene, SIR2. SIR4, essential for other silenced loci, paradoxically inhibits rDNA silencing. In this study, we elucidate a re...

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Journal: :Nature Reviews Genetics 2011

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Journal: :eLife 2019

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Journal: :Nature Biotechnology 1999

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