Adenosine deaminase (ADA) is an important regulator of insulin action. The single nucleotide polymorphism (SNP) G22A in the ADA gene decreases enzymatic activity of ADA. The aim of this study was to investigate the relationship between the SNP G22A and blood glycemic control, insulin resistance, and obesity of gestational diabetes mellitus (GDM) patients in an Iranian population. SNP G22A was d...

This study was aimed of determining the relationship polymorphism growth hormone receptor gene with some traits (daily rate, relative and specific growth, ratio efficiency feed conversion) in 45 samples common carp (Cyprinus carpio). The following are most important results obtained: DNA sequencing single nucleotide (SNP) showed there three mutations sites C24074T, A24375G G24485A. No genetic m...

The objective of this study was to search for single nucleotide polymorphism (SNP)-type polymorphisms in the dopamine D1 receptor in West Azerbaijani native chicken and look for their association with egg production and body weight traits of chickens by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP). For this purpose 180 blood samples were taken from nativ...

Proper management and genetic monitoring of the modern European bison (Bison bonasus) population is one most important responsibilities for this species’ conservation. Up-to-date, complex analysis performed using a consistent molecular method needed as tool to further validate maintain diversity species. The identification line when pedigree data are missing, well parentage individuals, crucial...

background: hypospadias is one of the most common congenital abnormalities in the male which is characterized by altered development of urethra, foreskin and ventral surface of the penis. androgen receptor gene plays a critical role in the development of the male genital system by mediating the androgens effects. objective: in present study, we looked for new variations in androgen receptor pro...

Background: Coronary artery disease (CAD) is a multifactorial and heterogenic disease. Recently, genome-wide association studies have reported that rs1333040 (C/T) and rs1004638 (A/T) single nucleotide polymorphisms (SNPs) in the 9p21 locus have very strong association with CAD. This study aimed to examine these associations in Southwest of Iran. Methods: Blood samples were collected from 200 C...

The aim of this study was to investigate influence of the NFE2L1 gene polymorphisms on some parameters of meat production in sheep. Polymorphisms of the NFE2L1 gene were detected using NimbleGen sequencing technology (Roche, USA). The effect of polymorphisms identified was investigated in Manych Merino sheep breed. In coding and regulatory parts of gene 11 single nucleotide polymorphisms (SNP) ...

A recent chordoma cancer genotyping study reveals that the rs2305089, a single nucleotide polymorphism (SNP) located in brachyury gene and a key gene in the development of notochord, is significantly associated with chordoma risk. The brachyury gene is believed to be one of the key genes involved in the pathogenesis of chordoma, a rare primary bone tumor originating along the spinal column or a...