Few finance theories consider the influence of "skewness" (or large and asymmetric but unlikely outcomes) on financial choice. We investigated the impact of skewed gambles on subjects' neural activity, self-reported affective responses, and subsequent preferences using functional magnetic resonance imaging (FMRI). Neurally, skewed gambles elicited more anterior insula activation than symmetric ...

Pooling specimens prior to performing laboratory assays has various benefits. Pooling can help to reduce cost, preserve irreplaceable specimens, meet minimal volume requirements for certain lab tests, and even reduce information loss when a limit of detection is present. Regardless of the motivation for pooling, appropriate analytical techniques must be applied in order to obtain valid inferenc...

The choice of bandwidth is crucial in the nonparametric estimation procedure. A number of methods to choose the associated bandwidth have been developed. In this paper we studied three existing bandwidth selectors for local linear regression with different design matrix characteristics. The performances illustrate that although there is no uniformly dominating rule, the variable bandwidth selec...

Identifying locations that exhibit the greatest potential for safety improvements is becoming more and more important because of competing needs and a tightening safety improvement budget. Current crash modeling practices mainly target changes at the mean level. However, crash data often have skewed distributions and exhibit substantial heterogeneity. Changes at mean level do not adequately rep...

introduction: x chromosome inactivation (xci) is a process during which one of the two x chromosomes in female human is silenced leading to equal gene expression with males who have only one x chromosome. here we have investigated xci ratio in females with opioid addiction to see whether xci skewness in women could be a risk factor for opioid addiction. methods: 30 adult females meeting dsm iv ...

X-chromosome inactivation (XCI) is the process in which one of the two copies of the X-chromosome in females is randomly inactivated to achieve the dosage compensation of X-linked genes between males and females. That is, 50% of the cells have one allele inactive and the other 50% of the cells have the other allele inactive. However, studies have shown that skewed or nonrandom XCI is a biologic...

In this article, we establish properties that relate quantiles of the log-skew-normal distribution to its parameters, allowing us investigate relationship between a positive skewed response variable and set explanatory variables via linear regression model. We compute maximum likelihood estimates parameters through correspondence skew-normal models. Monte Carlo simulations show satisfactory per...

This study aims to identify the best model of low birth weight by applying and comparing several methods based on quantile regression method's modification. The data is violated with linear assumptions; thus, approaches are used. adjusted combining it Bayesian approach since method can produce in small size samples. Three kinds modified considered here regression, Lasso Adaptive regression. art...