نتایج جستجو برای: skin substitutes
تعداد نتایج: 201103 فیلتر نتایج به سال:
Reconstructive surgery following skin tumor resection can be challenging. Treatment options after removing the tumor are skin grafting, local pedicled and axial flaps, or microsurgery for complex and extensive wounds correction. Recently, the use of dermal substitutes has been extended to reconstructive surgery in cutaneous oncology. Objectives. To report both a single-center experience using d...
Chronic wounds in skin persist because the normal process of wound healing is obstructed. Failures occur in the inflammation and proliferation phases of wound healing that reduce formation of granulation tissue and prevent epithelial migration to close the wound, resulting mostly from vascular insufficiencies of multiple etiologies. Microbial contamination of chronic wounds also contributes imp...
A Large scale of full-thickness skin defects is lack of auto-grafts and which requires the engineered skin substitutes for repair and regeneration. One major obstacle in skin tissue engineering is to expand epidermal stem cells (ESCs) and develop functional substitutes. The other one is the scaffold of the ESCs. Here, we applied type I collagen-modified chitin membrane to form collagen-chitin b...
Skin cancer is the most prevalent human and has presented a considerable world incidence rate increase over last years. While animals offer highly complex systems to study skin biology, ethical concerns differences found between animal have promoted development of alternative methods. In this review, we provide an overview important models describe advantages in vitro substitutes ex vivo models...
OBJECTIVE We hypothesize that the pathogen-free NIKS human keratinocyte progenitor cell line cultured in a chimeric fashion with patient's primary keratinocytes would produce a fully stratified engineered skin substitute tissue and serve to deliver autologous keratinocytes to a cutaneous wound. SUMMARY OF BACKGROUND DATA Chimeric autologous/allogeneic bioengineered skin substitutes offer an i...
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