To study the effects of neuroleptic therapy on sleep EEG variables in schizophrenia, as well as the clinical correlates of these variables, we performed polysomnographic (PSG) studies on 14 schizophrenic inpatients before and during neuroleptic therapy. Sleep continuity measures improved after 3 weeks of neuroleptic therapy, showing decreased sleep latency and improved sleep efficiency. REM lat...

INTRODUCTION This study evaluated dose-response effects of tiagabine on sleep in adults with primary insomnia. METHODS Men and women with primary insomnia (DSM-IV-TR) were randomly assigned to receive tiagabine 4, 6, 8, 10 mg or placebo in a randomized, double-blind, parallel-group study. Efficacy was assessed using polysomnography and self-report measures. Safety analyses included measures o...

The present study examined the associations of sleep patterns with multiple measures of academic achievement of undergraduate university students and tested whether sleep variables emerged as significant predictors of subsequent academic performance when other potential predictors, such as class attendance, time devoted to study, and substance use are considered. A sample of 1654 (55% female) f...

Abstract Sleep is an essential requirement for both physiological and psychological functioning has impact on various health parameters. The present study aimed to examine how quantity quality of sleep predicts burnout well-being by using self-reported objectively collected data. participants were 104 white-collar workers who wore a fitness tracker 14 consecutive days filled out questionnaire a...

OBJECTIVES/HYPOTHESIS Gastroesophageal reflux disease and heartburn negatively impact sleep; the impact of extraesophageal reflux (EER) symptoms on sleep is unknown. This study's goal was to evaluate the association of EER and measures of nasal obstruction, mood, insomnia, hypersomnia, and obstructive sleep apnea (OSA) risk. STUDY DESIGN Cross-sectional study. SETTING Tertiary care hospital...

Fifty-nine adults slept five nights with an Actigraph and answered two questionnaires related to sleeping quality and morningness/eveningness preferences. Next they performed a computerized attention task (the mathematics continuous performance test (MATH-CPT)) to assess various measures of attention. Results showed significant correlations between six attention variables and two measures of sl...

STUDY OBJECTIVES The ratio between the heart-rate increment to total power spectral density (%VLFI) has been introduced as a sensitive measure of sleep-related breathing disorders (SRBD). Since a complex interaction is present between sleep disorders and occurrence of arousals, we hypothesized that %VLFI and other indexes of heart-rate variability (HRV) measures reflect the degree of sleep frag...