Using phage display and IgG of a goat infected with Caprine Arthritis Encephalitis Virus (CAEV) we obtained families of 7 mer constrained peptides with consensus motifs LxSDPF/Y and SWN/KHWSY and mapped the epitopes mimicked by them at the Env 6-LISDPY-11 and 67-WNTYHW-72 sites of the mature gp135 amino acid sequence. The first epitope fell into the N-terminal immunogenic aa1-EDYTLISDPYGFS- aa1...

Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) expression (transcript levels) and proviral load in virus target tissues (lung, mammary gland, CNS and carpal joints). Control sheep were SRLV-seropositive asymptomatic (n = 3)...

The envelope glycoprotein of small ruminant lentiviruses (SRLV) is a major target of the humoral immune response and contains several linear B-cell epitopes. We amplified and sequenced the genomic segment encoding the SU5 antigenic site of the envelope glycoprotein of several SRLV field isolates. With synthetic peptides based on the deduced amino acid sequences of SU5 in an enzyme-linked immuno...

The small-ruminant lentiviruses ovine maedi-visna virus (MVV) and caprine arthritis-encephalitis virus (CAEV) cause encephalitis, progressive pneumonia, arthritis, and mastitis in sheep and goats. Icelandic MVV strains, which are lytic in tissue culture, have a wide species distribution of functional receptors, which includes human cells. In contrast, functional receptors for the nonlytic CAEV ...

Livestock have made major contribution to human societies by providing food, shelter, fuel, and services.  Sheep and goat are economically important livestock play an important socioeconomic role for small and large farmers in Libya.  Small ruminant animal meat is popular for Libyan customers, and demand is particularly high during religious and cultural festivals.  Small ruminants is valued fo...

Livestock have made major contribution to human societies by providing food, shelter, fuel, and services.  Sheep and goat are economically important livestock play an important socioeconomic role for small and large farmers in Libya.  Small ruminant animal meat is popular for Libyan customers, and demand is particularly high during religious and cultural festivals.  Small ruminants is valued fo...

livestock have made major contribution to human societies by providing food, shelter, fuel, and services.  sheep and goat are economically important livestock play an important socioeconomic role for small and large farmers in libya.  small ruminant animal meat is popular for libyan customers, and demand is particularly high during religious and cultural festivals.  small ruminants is valued fo...