A large body of evidence indicates that solar ultraviolet-B (UVB) irradiance and vitamin D reduce the risk of incidence and death for many types of cancer. However, most of that evidence comes from midlatitude regions, where solar UVB doses are generally high in summer. Data on cancer standardized incidence ratios (SIRs) by sex and 54 occupation categories based on 1.4 million male and 1.36 mil...

Vitamin D has emerged as a promising anti-cancer agent due to its diverse biological effects on tumor differentiation, apoptosis and suppression of cellular proliferation. Current evidence suggests a protective role of vitamin D in colon cancer. The effect of vitamin D on esophageal cancer remains controversial. Multiple studies investigated the association between vitamin D and esophageal canc...

Vitamin D sufficiency is required for optimal health, and solar ultraviolet B (UVB) irradiance is an important source of vitamin D. UVB and/or vitamin D have been found in observational studies to be associated with reduced risk for over a dozen forms of cancer, multiple sclerosis, osteoporotic fractures, and several other diseases. On the other hand, excess UV irradiance is associated with adv...

Skin cancers are one of the most common types cancer in United States [1], and melanoma has steadily increased over last 20 years. Solar ultraviolet radiation (UVR) is known as main cause damaging effects to skin [2], yet also preventable risk factor. Outdoor physical activity, an important health behavior, exposes body UVR thus ostensibly linked increases sunburn, melanoma, non-melanoma [3], [...

Prostate cancer is the second common cancer in men worldwide. The prevention of prostate cancer remains a challenge to researchers and clinicians. Here, we review the relationship of vitamin D and sunlight to prostate cancer risk. Ultraviolet radiation of the sunlight is the main stimulator for vitamin D production in humans. Vitamin D's antiprostate cancer activities may be involved in the act...

We analyzed data from the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study to test the hypothesis that vitamin D from sunlight exposure, diet, and supplements reduces the risk of breast cancer. We identified 190 women with incident breast cancer from a cohort of 5009 white women who completed the dermatological examination and 24-h dietary recall conducted fr...

Vitamin D is a hormone produced in the skin by ultraviolet radiation and plays crucial role calcium homeostasis. It has been lately acknowledged that vitamin participates pathophysiology of various chronic diseases its deficiency linked to deterioration patients’ condition. The aim this study was record levels 25(OH)D population rural, near-border area Northern Greece investigate possible assoc...