Somatosensory feedback plays a critical role in the coordination of articulator movements for speech production. In response to unexpected resistance to lip or jaw movements during speech, fluent speakers can use the difference between the somatosensory expectations of a speech sound and the actual somatosensory feedback to adjust the trajectories of functionally relevant but unimpeded articula...

We recorded somatosensory evoked magnetic fields from eight healthy subjects with a 122-channel whole-scalp SQUID magnetometer. The stimulus sequence consisted of 'standard' stimuli (85%) delivered to palmar side of the left thumb with an interstimulus interval of 0.6 s and of 'deviants' (15%), randomly interspersed among the standards, to little finger, and vice versa. Both stimuli activated f...

Abstract High-throughput single-cell epigenomic assays can resolve cell type heterogeneity in complex tissues, however, spatial orientation is lost. Here, we present combinatorial indexing on Microbiopsies Assigned to Positions for the Assay Transposase Accessible Chromatin, or sciMAP-ATAC, as a method highly scalable, spatially resolved, profiling of chromatin states. sciMAP-ATAC produces data...

PURPOSE The brain is a highly interconnected neuronal assembly in which network analyses can greatly enlarge our knowledge on seizure generation. The cortico-thalamo-cortical network is the brain-network of interest in absence epilepsy. Here, network synchronization is assessed in a genetic absence model during 5 s long pre-ictal->ictal transition periods. METHOD 16 male WAG/Rij rats were equ...