Andrew Donald Booth (1918-2009) was the leader of a team of computer pioneers at Birkbeck College in the University of London, UK. Booth worked with limited resources, both human and financial, and concentrated on building smaller machines. This paper presents an outline of his career in the UK which, the author believes, has not received the attention it deserves in comparison to a number of h...

Neurosurgery is considered to be one of the most challenging of all careers, as captured by the cliché, “it’s not brain surgery”. While the neurosurgeons who spoke to MJA reers for this issue’s Career Overview ry did emphasise the technical demands their specialty, they also said the clinical d cognitive challenges of neurosurgery re part of its appeal (page C1). Medical ntor focuses on neurosu...

Citation Merabet, Lotfi B., Kathryn J. Devaney, Corinna M. Bauer, Aparna Panja, Gena Heidary, and David C. Somers. 2016. “Characterizing Visual Field Deficits in Cerebral/Cortical Visual Impairment (CVI) Using Combined Diffusion Based Imaging and Functional Retinotopic Mapping: A Case Study.” Frontiers in Systems Neuroscience 10 (1): 13. doi:10.3389/fnsys.2016.00013. http://dx.doi.org/10.3389/f...

Abstract A consensus has not yet been reached regarding the accuracy of people with schizophrenia in self-reporting their real-life functioning. In a large ( n = 618) cohort stable, community-dwelling patients we sought to: (1) examine concordance patients’ reports functioning key caregiver; (2) identify which patient characteristics are associated to differences between and informants. Patient...

Previously thought to be primarily a structural component of nucleic acids, the pentose, D-ribose, in the form of the ester, ribose 5-phosphate, has now been shown to be an important intermediate in the pentose phosphate pathway of glucose metabolism. The sequence of the reactions of this pathway has been summarized by Horecker and Mehler (1) and Wood (2), and surveys of its significance in var...

The effect of D-mannose (Man) on plant cells was studied in two different systems: Arabidopsis roots and maize (Zea mays) suspension-cultured cells. In both systems, exposure to D-Man was associated with a subset of features characteristic of apoptosis, as assessed by oligonucleosomal fragmentation and microscopy analysis. Furthermore, D-Man induced the release of cytochrome c from mitochondria...