On the title page (page 3596), eighth author's initials were incorrect; correct name is K. L. Ingvartsen. In footnote, 3 authors inadvertently omitted from GplusE Consortium. The corrected listing given here (corrections in bold): Authors Consortium: Niamh McLoughlin, Alan Fahey, Elizabeth Matthews, Andreia Santoro, Colin Byrne, Pauline Rudd, Roisin O'Flaherty, Sinead Hallinan, Claire Wathes, Z...

Many blame the recent financial market turmoil on ratings agencies. We develop an equilibrium model of the market for ratings and use it to examine popular arguments about the origins of and cures for ratings inflation. In the model, asset issuers can shop for ratings – observe multiple ratings and disclose only the most favorable – before auctioning their assets. When assets are simple, agenci...

This year’s ISMB conference, an annual event organised by the International Society for Computational Biology (http://www.iscb.org) was the biggest ever, with over 1400 delegates. The venue was also a first, situated, as it was, in Copenhagen’s Tivoli Gardens funfair. However there was still time for the many satellite meetings that flanked the conference including the Bio Pathways conference, ...

and traveling salesman. A little background in molecular As we swim in a sea of data—both genomic and microarbiology would also be helpful. There is a brief chapter ray—we need good computational tools to understand titled “All You Need to Know about Molecular Biology,” the biological significance of the information we generbut its first sentence is “Well, not really, of course, see ate. One su...

A number of philosophers and writers have eloquently expressed the importance of understanding the past. “If you would understand anything, observe its beginning and its development” Aristotle “History teaches everything including the future” Alphonse Lamartine “Life must be lived forward, but it must be understood backward” Soren Kierkegaard “Those who cannot remember the past are condemned to...

eukaryotic cells (Pearl and Prodromou, 2002). Rather than acting at an early stage of folding, Hsp90 binds client proteins in a substantially folded form and faciliBarry Panaretou,1 Giuliano Siligardi,2 Philippe Meyer,3 Alison Maloney,4 Janis K. Sullivan,1 Shradha Singh,3 Stefan H. Millson,5 Paul A. Clarke,4 tates their association with cofactors or other proteins Soren Naaby-Hansen,5,6 Rob Ste...

Economic sanctions have the reputation of harming the population in the sanctioned countries. In this paper, I investigate under what circumstances such harm occurs and what is its magnitude. I estimate the impact of in utero exposure to sanctions episodes on infant weight, child height, and child mortality. Using a large child level data set from 69 countries, I …nd that being exposed to sanct...

It is with great pleasure and pride that I introduce to you this special issue of papers presented at the 10th Annual Conference of ENBIS, The European Network for Business and Industrial Statistics. The conference was held at the beautiful location of the University of Antwerp with Professor Martina Vandebroek as the Programme Committee chair and Professor Peter Goos as the Organising Committe...

Background: Remission, LDA and LDAS have been proposed as treatment goals for SLE. However, the independent impact of these states on damage accrual has not fully evaluated. Objectives: To determine remission (both off & treatment), LDA, LLDAS accrual. Methods: We studied a long-term longitudinal multinational SLE cohort, including patients completing at least two annual assessments. Remiss...

reviewers: Daniel Abramowicz, Belgium Peter Ackrill, UK Dwomoa Adu, UK Alberto Albertazzi, Italy Pedro Aljama, Spain Paolo Altieri, Italy Anders Alvestrand, Sweden Alessandro Amore, Italy Björn Anderstam, Sweden Michele Andreucci, Italy Vittorio E. Andreucci, Italy Margret Arnadottir, Iceland Jan Aten, Netherlands Per-Ola Attman, Sweden Jonas Axelsson, Sweden Bert Bammens, Belgium Ali Basci, Tu...