OBJECTIVE To study the morphological features in breast carcinoma which have proven prognostic value. METHODS AND SETTING A retrospective analysis of 572 mastectomy specimens received over a period of three years at the department of pathology, The Aga Khan University Hospital. RESULTS A total of 572 mastectomy specimens were analyzed which were received over a period of three years. Most o...

The differences between invasive lobular and ductal carcinomas affect the diagnostic and therapeutic management for patients with breast cancer. In most cases, this can be accomplished because of distinct histomorphologic features. However, occasionally, this task may become quite difficult, in particular when dealing with the variants of infiltrating lobular carcinoma. Lobular carcinoma has be...

Purpose: The role of infiltrating B cells in hepatocellular carcinoma has been overlooked formany years. This study is aimed to delineate the distribution, prognostic value, and functional status of B cells in human hepatocellular carcinoma. Experimental design: Immunohistochemistry was used to investigate the distribution and clinical significance of infiltrating CD20þ B cells in a series of 1...

STUDY OBJECTIVE The aim of the study was to evaluate the effectiveness of a centralised population based cervical cytology screening programme. DESIGN The study was a case-control investigation. SETTING Cases and controls were confined to the province of Florence. PARTICIPANTS 191 out of 208 cases of cervical cancer in women less than 75 years old at diagnosis in the period 1982-85 were i...

background and objectives: breast cancer is the most common malignancy among women in the world. the aim of this study was to assess estrogen receptor (er), progesterone receptor (pr) and her-2/neu of infiltrating ductal carcinoma (idc) with tumor size, histologic grade, lymph node metastasis and age. methods: this study was carried out on 300 tissue blocks ofpatients with idc who underwent mas...

Tubular Carcinoma (TC) of the breast, also known as tubular carcinoma or well-differentiated adenocarcinoma, is defined a special type breast cancer consisting structures with excellent prognosis by WHO (2019) pathological and genetic classification neoplasms. Two cases admitted to our hospital were reported. The relevant literature was reviewed clinical features, histological morphology (micro...

Ovarian cancer is the leading cause of death from gynaecological cancers worldwide. In Georgia, ovarian ranks fourth in terms prevalence, and third mortality rate. According to latest epidemiological data, there will be 21,421 new cases 13,770 deaths United States 2021. Due lack early screening methods asymptomatic clinical courses, most diagnosed at an advanced stage, when prognosis disease al...

squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. most of the reported cases have had a component of adenocarcinoma. we report a 70-year-old man who presented with acute onset right upper quadrant pain. he operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. histop...