نتایج جستجو برای: specific phenotype

تعداد نتایج: 1163345  

Fazel Shokri, Hassan Vahidnezhad, Hojatollah Rabbani, Leila Youssefian, Mahmoud Jeddi-Tehrani, Mina Tabrizi , Mohammad Mehdi Akhondi,

Backgrounds: Evidence is accumulating to support disruption of tissue architecture as a powerful event in tumor formation. For the past four decades, intensive cancer research with the premise of “cancer as a cell based-disease” focused on finding oncogenes or tumor suppressor genes. However, the role of the tissue architecture was neglected. Three dimensional (3D) cell cultures which can recap...

Maryam Ayatollahi, Maryam Borhani-Haghighi Tahereh Talaei-Khozani Zahra Vojdani,

Background: Wharton’s jelly is an unlimited source of stem cells that can be used in cell therapy and tissue engineering without any ethical concern. It has been revealed the cell-free extract could be effective to induce cell differentiation. The objective of this study was to induce Wharton’s jelly-derived mesenchymal stem cells (MSCs) into hepatocyte-like cells by premeabilization of the cel...

2010
Stacia R. Engel Rama Balakrishnan Gail Binkley Karen R. Christie Maria C. Costanzo Selina S. Dwight Dianna G. Fisk Jodi E. Hirschman Benjamin C. Hitz Eurie L. Hong Cynthia J. Krieger Michael S. Livstone Stuart R. Miyasato Robert S. Nash Rose Oughtred Julie Park Marek S. Skrzypek Shuai Weng Edith D. Wong Kara Dolinski David Botstein J. Michael Cherry

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org) is a scientific database for the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast. The information in SGD includes functional annotations, mapping and sequence information, protein domains and structure, expression data, mutant phenotypes, physical and gen...

2012
Georgios V. Gkoutos Robert Hoehndorf

Ontologies are widely used in the biomedical community for annotation and integration of databases. Formal definitions can relate classes from different ontologies and thereby integrate data across different levels of granularity, domains and species. We have applied this methodology to the Ascomycete Phenotype Ontology (APO), enabling the reuse of various orthogonal ontologies and we have conv...

Journal: :Journal of lung, pulmonary & respiratory research 2021

Background: Recent literature suggests respiratory system compliance (Crs) based phenotypes exist among COVID-19 ARDS patients. We sought to determine whether these and Crs predicts mortality. Methods: A retrospective observational cohort study of 111 patients admitted March 11-July 8, 2020. was averaged for the first 72-hours mechanical ventilation. Crs<30ml/cmH2O defined as poor Crs(phenot...

Journal: :Alpine Botany 2021

Abstract Bacterial communities in the phyllosphere are shaped by host genotype and phenotype spatio-temporal variation of environment. In turn, bacteria have potential for altering plant phenotype. Field experiments can help to estimate bacterial effects on functional traits under natural conditions. We used a transplantation approach culturable explore how manipulation leaf-associated microbia...

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