typical nmo is characterized by simultaneous or sequential acute transverse myelitis and optic neuritis. spinal cord lesions extending over 3 or more vertebral segments and normal brain imaging are the typical mri findings in nmo. in typical cases with positive nmo antibody the diagnosis is easy but in seronegative and atypical cases with different clinical manifestations and mri features the d...

a high number of people in the world suffered from spinal cord injury (sci). spinal cord injuries are happen due to falls from height, accidents, climbing, sports and etc. emergency care according to the standards not performed immediately after sci. a significant enhancement in the number of mortality and complications was observed every year. the aim of this study is to prevent the mortality,...

Fiber tractography is a technique capable of depicting the three-dimensional structure and connectivity of nerve fibers using serial magnetic resonance diffusion tensor imaging (DTI). To establish fiber tractography and DTI methods in veterinary clinical medicine, we evaluated fiber tractography and DTI parameters: apparent diffusion coefficient (ADC) values and fractional anisotropy (FA) value...

background: the aim of this research was to study the distribution and changes of glycoconjugates particularly their terminal sugars by using lectin histochemistry during mouse spinal cord development. methods: formalin-fixed sections of mouse embryo (10-16 fetal days) were processed for lectin histochemical method. in this study, two groups of horseradish peroxidase-labeled specific lectins we...

UNLABELLED Primary spinal involvement in hematological diseases is rare. PURPOSE The purpose of this article is studying diagnostic and treatment strategies in patients with spinal cord primary hematologic tumors causing spinal cord compression syndrome. PATIENTS AND METHODS We report two cases with spinal cord primary hematologic tumors causing spinal cord compression syndrome. One patient...

Background: Amylin and Salmon Calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. The aim of this study was to characterize receptors for Amylin and Salmon Calcitonin functionally in the spinal cord of rats. We assessed the expression of c-Fos in response to intraplantar formalin in the lumbar regions of the spinal cord in consciou...

Acupuncture therapy is an essential part of traditional Chinese medicine that being recognized by increasing number countries due to its convenience, effectiveness, and low risk adverse reactions. The microenvironment important in the occurrence, development, treatment, rehabilitation diseases, has recently become a focus research field various diseases. Acupuncture’s therapeutic effect on huma...

Spinal cord compression due to extramedullary hematopoiesis is a well-known complication in a number of hematological diseases. Most of the patients present with progressive paraparesis due to the slow expansion of the extramedullary hematopoietic tissue. The authors report a case of chronic myeloproliferative disorder with spinal extramedullary hematopoiesis presenting with acute paraplegia. C...

background and objective: deprenyl is a drug for the treatment of parkinson’s disease, where the dopaminergic neurons are the target of this drug. several reports also documented that deprenyl has an effect on the sensory and motor neurons. there are some reports about the mode of action of deprenyl on motoneurons as a neuroprotective agent, while others believe that deprenyl acts as a neurores...

background ischemic injury of the spinal cord during the surgical repair of thoracoabdominal aortic aneurysms might lead to paraplegia. although a number of different mechanisms have been proposed, the exact cause of paraplegia has remained unknown, hampering the development of effective pharmacologic or other strategies for prevention of this condition. a number of studies suggested that cyclo...