traumatic central nervous system injuries lead to a severe and permanent neurological deficit. oligodendrocytes (olcs) are vulnerable to damage in a variety of neurologic diseases. although no effective therapeutic option is currently available, recent other studies have shown that cell therapeutic strategies hold promise to enhance functional recovery after injury. the aim of this study is to ...

introduction: worldwide, every year, many people undergo spinal cord injury which is of the worst health problems and is followed by several secondary complications. today, more than half of the world population is in danger of natural disasters such as earthquake, which is one of the causes of spinal cord injuries outbreak. earthquake in bam also caused many spinal cord injured people for whom...

materials and methods: young adult sprague-dawley rats (200-250g) were assigned into one of the three different groups of control, sci, and adenovirus transfer (ad) (n=3/ group). control rats received no injury, nor any surgery. for sci rats, sci was produced by a 10g brass rod with a tip diameter of 2 mm which was dropped from a height of 12.5 mm onto exposed spinal cord at level of t10 with n...

background: health-related quality-of-life (hr-qol) may be affected by various factors including injury-related characteristics among individuals with spinal cord injury (sci). however, the impact of the influence of these variables has not yet been fully described in iranian population. here, we assessed the relationships between injury-related characteristics and hr-qol among iranian people w...

Purpose: Individuals’ personal awareness and learning after spinal cord injury is one of the most important factors in patients’ confrontation with subsequent disabilities and new life style which affects their ultimate independence. This article is an abstracted result of a qualitative study on effective factors of independence among patients with spinal cord injury. Methods: This study a...

objectives major differences exist in the anatomy and biomechanics of the growing spine that causes failure patterns different from those in adults. spinal injury in the pediatric patient is a main concern because timely diagnosis and appropriate treatment can prevent further neurologic damage and deformity and potentiate recovery. we conducted a retrospective clinical study of 137 cases (93 bo...

background: recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (bmsc) transplantation. in this study, we made a comparison of intraspinal and intravenous route of bmsc administration to repair injured spinal cord tissue. methods: six groups of adult female rats were used in this study. laminect...

introduction deep vein thrombosis is one of the most important complications in patients with spinal cord injury. this study compares the effects of mechanical prophylaxis with or without pharmacological prophylaxis on prevention of deep vein thrombosis in patients with spinal cord injury. materials and methods we conducted a double blind clinical trial study with 75 cases. these patients were ...

the case is 43 years old woman referred to emergency department of our hospital with quadriplegia and severe respiratory insufficiency due to c5-c6 injury after falling. she discharged from icu after fixation of the lesion and successful weaning. we evaluated electrical activity of diaphragm signal (edi), respiratory drive (p100) during one month period. we detected increase in level of electri...

abstract introduction: cardiovascular fitness as the ability of the system - respiratory and skeletal muscle to achieve a certain level of activity is defined as, where after spinal cord injury can be reduced through exercise can increase this capacity. objective: the objective of this study, veterans with spinal cord injury spirometric indices in various athletic sports (archery, wheelchairran...