نتایج جستجو برای: splenocyte

تعداد نتایج: 796  

Journal: :Infection and immunity 1997
M G Schwacha T K Eisenstein

Studies from our laboratory have shown that infection of mice with an attenuated strain of Salmonella typhimurium causes a marked suppression in the capacity of splenocytes to generate an in vitro plaque-forming cell (PFC) response to sheep erythrocytes. The suppression has been shown to be mediated by mature, adherent macrophages (Mphis) and nonadherent, precursor Mphis. Nitric oxide has been ...

Journal: :Physiology & behavior 2004
Gregory E Demas Corey Johnson Kelly M Polacek

Social interactions can have pronounced effects on reproductive physiology and behavior in a wide range of species. Much less is known about the effects of social interactions on immunity. The goal of the present study was to test the effects of social interactions on both reproductive and immune responses in Siberian hamsters (Phodopus sungorus). Male and female hamsters were housed alone, in ...

Journal: :Journal of the Chinese Medical Association : JCMA 2007
Yuh-Min Chen Pi-Sheng Wang Jacqueline Ming Liu Yi-Lin Hsieh Chun-Ming Tsai Reury-Perng Perng Jacqueline Whang-Peng

BACKGROUND We used B16-F10 (B16) melanoma tumor cells and syngeneic C57BL/6 (B6) mice as a study model for pulmonary metastases, to better understand whether or not there exist differences in tumorigenicity and in the effectiveness of immunotherapy as a function of host age (1-, 3-, 12- and 24-month-old). METHODS Intravenous injection of B16 melanoma cells were administered to B6 mice of diff...

Journal: :Journal of immunology 2010
Bing Zhang Sandhya Subramanian Suzan Dziennis Jia Jia Masayoshi Uchida Kozaburo Akiyoshi Elton Migliati Anne D Lewis Arthur A Vandenbark Halina Offner Patricia D Hurn

Reduced risk and severity of stroke in adult females is thought to depend on normal endogenous levels of estrogen, a well-known neuroprotectant and immunomodulator. In male mice, experimental stroke induces immunosuppression of the peripheral immune system, characterized by a reduction in spleen size and cell numbers and decreased cytokine and chemokine expression. However, stroke-induced immun...

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