Gaussian split Ewald (GSE) is a versatile Ewald mesh method that is fast and accurate when used with both real-space and k-space Poisson solvers. While real-space methods are known to be asymptotically superior to k-space methods in terms of both computational cost and parallelization efficiency, k-space methods such as smooth particle-mesh Ewald (SPME) have thus far remained dominant because t...

Title of dissertation: INTEGER PROGRAMMING-BASED HEURISTICS FOR VEHICLE ROUTING PROBLEMS Damon J. Gulczynski Doctor of Philosophy, 2010 Dissertation directed by: Professor Bruce Golden Applied Mathematics and Scientific Computation Robert H. Smith School of Business The vehicle routing problem (VRP) has been an active field of study by operations researchers for over 50 years. Many practical ap...

We consider a cement delivery problem with an heterogeneous fleet of vehicles and several depots. The demands of the customers are typically larger than the capacity of the vehicles which means that most customers are visited several times. This is a split delivery vehicle routing problem with additional constraints. We first propose a two phase solution method that assigns deliveries to the ve...

DevOps is an emerging paradigm to eliminate the split and barrier between developers and operations personnel that traditionally exists in many enterprises today. The main promise of DevOps is to enable continuous delivery of software in order to enable fast and frequent releases. This enables quick responses to changing requirements of customers and thus may be a critical competitive advantage...

This paper examines a manufacturer’s integrated planning problem for the production and the delivery of a set of orders. The manufacturer in this setting can use two vehicle types for outbound shipments. The first type of vehicle is available in unlimited numbers, but expensive. The second type, which is relatively low in its price, has limited and time-varying availability. We analyze the manu...

Context-aware systems that rely on mobile devices for user interaction must address the low bandwidth of both communications and more importantly the user’s limited attention, which will typically be split between several competing tasks. Content delivery in such systems must be adapted closely to users’ evolving situations and shifting priorities, in a way that cannot be accomplished using sta...

Split reporter-based bioluminescence imaging is a useful strategy for studying protein-protein as well as other intracellular interactions. We have used a combinatorial strategy to identify a novel split site for firefly luciferase with improved characteristics over previously published split sites. A combination of fragments with greater absolute signal with near-zero background signals was ac...

In this paper, we discuss an extension of split cuts that is based on widening the underlying disjunctions. That the formula for deriving intersection cuts based on splits can be adapted to this case has been known for a decade now. For the first time though, we present applications and computational results. We further discuss extensions of the existing theory with respect to cut strengthening...