BACKGROUND The human leukocyte antigen (HLA) system is widely used as a strategy in the search for the etiology of renal function impairment. OBJECTIVES This study was carried out to detect the most common HLA alleles' distribution in kidney transplant in both donors and recipients, and clarify the association between HLA alleles and renal dysfunction immediately after transplantation. PATI...

XPERIMENTAL evidence from studies in several fungi has demonstrated E that intragenic recombination is predominantly non-reciprocal whereas intergenic recombination is primarily reciprocal. These observations have led to studies to determine whether intragenic and intergenic recombination derive from the same or different mechanisms. In recent years experimental data supporting both interpretat...

Previously, we have reported the results of our retrospective study on the effect of HLA class II allele matching on the outcome of corneal transplant. Here, we demonstrate our findings of the study for HLA class I allele matching in the same study subjects. Eighty transplant recipients were typed for HLA-A, and 79 transplant recipients were typed for HLA-B alleles, by PCR-SSOP. The association...

AIMS To investigate whether education level of family members predicts all-cause and cardiovascular death and initial-episode peritonitis in patients on peritoneal dialysis (PD). METHODS A total of 2264 patients on chronic PD were collected from seven centers affiliated with the Socioeconomic Status on the Outcome of Peritoneal Dialysis (SSOP) Study. All demographic, socioeconomic and laborat...

PURPOSE To investigate the association of the HLA-A, -B and -DRB1 alleles with the occurrence of Recurrent Spontaneous Abortion. METHODS A case-control study of 200 women aged 18 to 35 years, consisting of a convenience sample of 100 women who had idiopathic recurrent spontaneous abortion and 100 women without abortion and with two or more children. Peripheral blood genomic DNA was extracted ...

Poster presentation Some autistic children also have symptoms of depression, anxiety or obsessive-compulsive disorder (OCD). Aromatic anti-epileptic drugs (AEDs) may be used as a mood-stabilizing medication to treat these symptoms, including carbamazepine (CBZ), oxcarbazepine (OXCBZ), and lamotrigene (LMG). Moreover, one in every four autistic spectrum disorder children have seizures, the use o...

UNLABELLED Biomarkers provide certain values for diagnosis, monitor treatment efficacy, or for the development of novel therapeutic approach for particular diseases. Thus, the identification of specific of biomarkers for specific medical problems, including malignant diseases may be valuable in medical practice. In the study, we have used the Wilms' tumor gene (WT1) as a biomarker to evaluate i...

Introduction Beef carcasses, which are initially sterile, become contaminated with bacterial pathogens via transmission of organisms from the exterior of the live animal, and/or from the environment, to the product surface. Extensive contamination, or abusive conditions that allow bacteria to reproduce, increase risk for presence of pathogenic bacteria and formation of toxins in food (Sofos et ...

BACKGROUND There are 3 classes of HLA molecules; HLA class I, II and III, of which different classes have different functions. HLA-B gene which belongs to HLA class I play an important role predicting drug hypersensitivity. MATERIALS AND METHODS Nine hundred and eighty-six Thai subjects who registered at a pharmacogenomics laboratory were determined for HLA-B genotype using a two-stage sequen...

AIMS To investigate whether uric acid (UA) is an independent predictor of cardiovascular (CV) and all-cause mortality in peritoneal dialysis (PD) patients after controlling for recognized CV risk factors. METHODS A total of 2264 patients on chronic PD were collected from seven centers affiliated with the Socioeconomic Status on the Outcome of Peritoneal Dialysis (SSOP) Study. All demographic ...