PURPOSE A multivariate analysis is used to determine the predictive value of pretreatment clinical indicators on pathologic features associated with local failure after radical prostatectomy in patients with prostate cancer. METHODS AND MATERIALS A retrospective review of the pathologic findings of 235 patients with adenocarcinoma of the prostate treated between 1990 and 1993 with a radical r...

BACKGROUND Modern approach to the surgical treatment of Hirschsprung's disease (HD) consists in earliest possible repair and reduction number interventions. Primary one-stage transanal endorectal pull-through (TEPT) technique requires preoperative determination length aganglionic segment. The efficacy standard method - contrast enema is questionable patients with a poorly defined transitional z...

Diarrhoea and perianal excoriation occur frequently after the endorectal pull-through operation for Hirschsprung's disease. A new method of faecal analysis was performed on 3-day stool collections in 17 postoperative Hirschsprung patients and in 14 normal children, in order to define the faecal abnormality and to establish the cause of perianal excoriation in these patients. Loose stools in pos...

We report a protracted hypoxic event during Soave's endorectal pull-through for Hirschsprung's disease in a 2-month-old male infant with tetralogy of Fallot. After the bowel loops were delivered out of the abdominal cavity, profound hypoxemia occurred which persisted for about 120 min. The hypoxemia was completely resolved after the intestine was reduced back into the peritoneal cavity. The imm...

OBJECTIVE To compare outcomes following totally transanal endorectal pull-through (TTERPT) versus pull-through with any form of laparoscopic assistance (LAPT) for infants with uncomplicated Hirschsprung's disease. DESIGN Systematic review and meta-analysis. SETTING Five hospitals with a paediatric surgical service. PARTICIPANTS 405 infants with uncomplicated Hirschsprung's disease. INTE...

BACKGROUND After resection of long-segment Hirschsprung's disease, severe perianal dermatitis (SPAD) may occur because of high stool frequency and elevated concentrations of fecal pancreatic proteases. We investigated prospectively the effect of potato-derived protease inhibitors (PPI) on skin conditions in children with postoperative SPAD. METHODS Four children (aged 12 to 24 months) with th...

In the treatment of locally advanced rectal cancer, preoperative chemoradiotherapy improved the rate of local recurrence after surgery and anal sphincter preservation [1]. Because it resulted in down-staging of tumors and changes of histologic characteristics, it is now regarded as the standard treatment in the patients with stages II-III advanced rectal cancer [2]. Conventional preoperative ch...

Anorectal innervation that governs sensation, motor function, and rectal accommodation can be influenced by the type of surgical procedure used to treat children with Hirschsprung disease. At our institution, we began to perform single-stage, laparoscopy-assisted transanal endorectal pull-through (LATEP) with submucosal dissection and anastomosis of the ganglionated bowel at 2 different levels ...