Bacterial resistance to antibacterial drugs in the treatment of some bacterial infections has become a menace, therefore causing untold health challenges to patients. The antibacterial activity of hot and cold water and ethanolic extract of the leaf and stem bark of Irvingia gabonensis against Escherichia coli and Staphylococcus aureus was evaluated using agar-well diffusion and agar dilution m...

BACKGROUND Chagas disease, amebiasis, giardiasis and trichomoniasis represent a serious health problem in Latin America. The drugs employed to treat these illnesses produce important side effects and resistant strains have appeared. The present study was aimed to evaluate the antiprotozoal activity of leaves, stem bark and root bark of Elaeodendron trichotomum, a celastraceus, that is used in M...

Today green synthesis of silver nanoparticles (SNPs) from plants is an utmost emerging filed in nanotechnology. In the present study, we have reported a green method for synthesis of SNPs from aqueous stem bark extract of Syzygium alternifolium, an endemic medicinal plant of South Eastern Ghats. These green-synthesised nanoparticles are characterised by colour change pattern, and the broad peak...

The electrophilic, free radical and reactive oxygen species scavenging and detoxification potentials of Lophiraalata stem bark was evaluated. L. alata stem bark effectively scavenged DPPH radical, superoxideion and hydrogen peroxide. It produced 88% scavenging effect of DPPH radical at a concentration of 1.0 mg/ml. Aqueous extract of L. alata-stem bark produced 76% and 92% scavenging effect on ...

Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stem-bark extract of Leuconotis griffithii. Alkaloids 1-4 showed moderate cytotoxicity against drug-sensitive and vincristine-resistant human KB cells.

From the stem bark hexanic extract of Garcinia chapelieri, chapexanthone A, B were isolated using combinations of column and thin-layer chromatographic methods. Their structures were elucidated by NMR spectroscopic methods, mainly 1D and 2D NMR.

Cissus populnea has been used locally to treat many ailments such as venereal, stomach and skin infections; and also used as laxative or purgative. Economically it has been used as binder in food and in lining dye pits. This work aims at determining the type of anthraquinones from the stem bark of C. populnea which might be a potential source of drugs (laxative/cathartic) using thin layer chram...

BACKGROUND The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as diarrhea, spasm, pneumonia and animals bite. Considering the ethnopharmacolog...

Abstract. A study on physicochemical characteristics of Ceiba petandra and Lannea kerstingii stem bark extracts cream being developed for the treatment of topical dermatophytic infections has been carried out to assure safe, effectiveness and stability during storage and usage. The stem barks of Ceiba petandra and Lannea kerstingii were extracted with methanol and ethyl acetate respectively. Th...

BACKGROUND The emergence of drug resistant pathogens becomes a crucial problem for infectious diseases worldwide. Among these bacteria, Pseudomonas aeruginosa is one of which highly resists to many currently used drugs and becomes a major concern in public health. Up till now, the search for potential antimicrobial agents has been still a challenge for researchers. METHODS Broth microdilution...