Video endoscopic images were used to investigate whether gastroenterologists could agree on the definition of lesions within the stomach seen at endoscopy, with particular reference to those seen in patients taking non-steroidal anti-inflammatory drugs. Seven experienced endoscopists, unaware of the patients' clinical history or drug consumption, recorded their classification for 93 randomised ...

Inflammation is a response of vascularized living tissue to the local injury. The severe side effects of steroidal and non-steroidal anti-inflammatory drugs evoked us to search for new anti-inflammatory drugs from the indigenous source. The methanol extract of leaves of Clerodendron infortunatum Linn. (MECI) was evaluated for anti-inflammatory activity against the carrageenan, histamine and dex...

OBJECTIVE To estimate the risk of adverse birth outcome in women who take non-steroidal anti-inflammatory drugs during pregnancy. DESIGN AND SETTING Population based cohort study and a case-control study, both based on data from a prescription registry, the Danish birth registry, and one county's hospital discharge registry. PARTICIPANTS COHORT STUDY: 1462 pregnant women who had taken up pr...

We report a prospective, randomised, controlled trial of the effect of either a non-steroidal anti-inflammatory drug (diclofenac sodium) or physiotherapy on the recovery of knee function after arthroscopy. At 42 days after surgery there was no significant benefit from either form of postoperative treatment compared with the control group. Complications attributable to the anti-inflammatory drug...

Anti-aromatase agents now have a central role in the management of breast cancer in postmenopausal women; they are superior to megestrol acetate as second-line therapy and to tamoxifen for initial therapy of metastatic disease. They also are highly active as neoadjuvant therapy. Two classes of anti-aromatase agents are available: steroidal (eg, exemestane) and nonsteroidal (eg, anastrozole, let...

Background: To explore the clinical efficacy, safety, and prevention of major adverse reactions non-steroidal anti-inflammatory drug celecoxib combined with OxyContin Pregabalin in treatment cancerous pudendal neuralgia.