introduction: neural stimulation is a promising new technology for the treatment of medically-intractable seizures.  transcranial magnetic stimulation (tms) is a simple, non-invasive, low cost technique which is widely used in neurophysiology. in a few studies that have been performed at different frequencies the therapeutic effects of this technique were not obvious. repetition of low frequenc...

background several lines of evidence suggest that early sensory stimulation and regular family visiting programs are potential nursing interventions to improve the outcomes of head injured comatose patients. however, little is known about the impacts of family involvement in providing sensory stimulation. objectives to determine the effects of a sensory stimulation program conducted by nurses a...

objective(s) sildenafil citrate is a new drug and has special properties that bring about nitric oxide effects on vascular smooth muscle. the aim of this study was to assess the effects of ovarian stimulation and sildenafil citrate injection on pinopode expression in mice. materials and methods thirty adult female mice were randomly divided into three groups: control, hyperstimulated and hypers...

background: release of vascular endothelial growth factor (vegf) by ovaries in response to hcg administration is one of the main mechanisms of ovarian hyper stimulation syndrome. since dopamine/dopamine receptor2 (dp-r2) pathway activity -mediated by vegf/ vascular endothelial growth factor receptor 2 (vegfr-2) signaling-, is associated with angiogenic events, dopamine agonists were used for th...

introduction: previous studies have been shown that low frequency stimulation (lfs) has an inhibitory effect on kindling acquisition. however, the mechanism of this effect has not been completely determined. in the present study, the effect of lfs of the perforant path on seizures induced by rapid perforant path kindling was investigated. methods: animals were kindled by electrical stimulation ...

conclusions when itbs was applied over the primary motor cortex, it significantly improved manual dexterity, but had no significant effect on the hand motor imagery ability in ms patients. results itbs group showed a reduction in the time required to complete the 9hpt (mean difference = -3.05, p = 0.002), and an increase in the number of blocks transferred in one minute in the bbt (mean differe...

introduction fetal movement started at the 7th weeks of pregnancy and by the end of pregnancy will gradually be perfect and harmonious. near-term fetuses can discriminate acoustic features, such as frequencies and spectra, and process complex auditory streams. in this study, we aimed to evaluate fatal movement in response to music and vibration stimulation. materials and methods this study is a...

the provision of an adequate quantity of cells with proper function and purity is one of the main challenges of tissue engineering studies. stem cells, with their self-renewal and differentiation capacity, are considered one of the main cell sources in the field of tissue engineering. previously, the use of chemical factors seemed to be the only possible way for stem cell differentiation. howev...

epilepsy is among the most common disorders of the central nervous system and there is not an absolute method for its treatment. it has been shown that each seizure has a depressing effect on the following seizure. thus, finding the mechanisms responsible in this phenomenon can improve our knowledge toward new ways for epilepsy treatment. in this study, the role of adenosine a1 receptors in pos...

advantages of mild-stimulation have long been appreciated, while there was a called for more patient-friendly approach in ovarian stimulation around 20 years ago (1)...