Abstract Psychostimulants such as amphetamine (AMPH) target dopamine (DA) neuron synapses to engender drug-induced plasticity. While DA neurons modulate the activity of striatal (Str) cholinergic interneurons (ChIs) with regional heterogeneity, how AMPH affects ChI has not been elucidated. Here, we applied quantitative fluorescence imaging approaches map dose-dependent effects a single dose on ...

BACKGROUND AND OBJECTIVE The aim of this study was to evaluate and compare various parameters between complete and incomplete ST-segment resolution (STR) patients' groups and to identify associates of STR in patients with acute ST-segment elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PPCI) (primary outcome). MATERIALS AND METHODS A total of 203 cons...

STR/N is an inbred strain of mice which is known to exhibit extreme polydipsia and polyuria. We previously found central administration of angiotensin II enhanced cardiovascular responses in STR/N mice than normal mice, suggesting that STR/N mice might exhibit different cardiovascular responses. Therefore, in this study, we investigated daily mean arterial blood pressure and heart rate, and cha...

Currently, mutations in three genes, namely rrs, rpsL, and gidB, encoding 16S rRNA, ribosomal protein S12, and 16S rRNA-specific methyltransferase, respectively, are considered to be involved in conferring resistance to streptomycin (STR) in Mycobacterium tuberculosis. The aim of this study was to investigate the spectrum and frequency of these mutations in M. tuberculosis clinical isolates, bo...

در این پژوهش سعی می‌­شود مدلی برای شبیه‌­سازی چرخه عمر صنعت برق با استفاده از شبیه‌سازی عامل­بنیان ارائه شود، مدل، 5 عامل استخراج شد و شبیه­‌سازی به کمک نرم‌افزار Anylogic صورت پذیرفت. بهینه‌­سازی مدل چهار سناریو نظر خبرگان شد. سناریوی نخست، جذابیت نیروگاه گازی سیکل ترکیبی کاهش یافت بر دو دیگر افزوده نتیجه افزایش تولید آبی است که توجه کمبود منابع کشور به‌صرفه نیست. دوم ورود یک فناوری جدید میزان...

Short tandem repeats (STRs) have a wide range of applications, including medical genetics, forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to profile hundreds of thousands of STR loci. However, mainstream bioinformatics pipelines are inadequate for the task. These pipelines treat STR mapping as gapped alignment, which results in cumbersome processing times a...

The aim of this study was to apply Speech-to-Text Recognition (STR) in an effort to improve learning performance in an online synchronous cyber classroom environment. Students’ perceptions and their behavioral intentions toward using STR and the effectiveness of applying STR in synchronous cyber classrooms were also investigated. After the experiment, students from the experimental group percei...

BACKGROUND Incomplete ST-segment resolution (STR) after successful primary angioplasty for acute myocardial infarction (AMI) is associated with a poor prognosis. We used intracoronary Doppler velocimetry to investigate whether incomplete STR after primary angioplasty is a marker of severe microcirculatory dysfunction. METHODS AND RESULTS Fifty patients with < or =12-hour AMI underwent success...

Neuronal nitric oxide synthase-expressing (nNOS+) GABAergic interneurons are common in hippocampal stratum (str.) radiatum. However, these cells are less well characterized than nNOS+ ivy cells in str. pyramidale or neurogliaform cells (NGC) in str. lacunosum-moleculare. Here we have studied the laminar distribution of the axons and dendrites, and the immunoreactivity of these neurons recorded ...

Single tablet regimens (STRs) for HIV infection improve patient satisfaction, quality of life, medication adherence, and virological suppression compared to multitablet regimens (MTRs). This is the first study assessing STR uptake and durability in Australia. This retrospective audit of all patients receiving an STR (n = 299) at a large Sydney HIV clinic (January 2012-December 2013) assessed pa...