The strain-induced reorientation response of cyclically stretched cells has been well characterized in uniform strain fields. In the present study, we comprehensively analyse the behaviour of human fibroblasts subjected to a highly non-uniform strain field within a polymethylsiloxane microdevice. Our results indicate that the strain gradient amplitude and direction regulate cell reorientation t...

The sufficient condition they came up with consists of two parts. They first assumed that f is a twice continuously differentiable function on [0, 1]n and introduced some shorthand notation. Let ‖ · ‖ denote the supremum norm. For each i and j, let fi = ∂f ∂xi and fij = ∂2f ∂xi∂xj (1.4) and define a = ‖f‖, bi = ‖fi‖, and cij = ‖fij‖. In addition to this minor smoothness condition on the functio...

In this paper we derive a strain gradient plate model from the three-dimensional equations of strain gradient linearized elasticity. The deduction is based on the asymptotic analysis with respect of a small real parameter being the thickness of the elastic body we consider. The body is constituted by a second gradient isotropic linearly elastic material. The obtained model is recognized as a st...

Gradient nano-grained (GNG) metals are a unique class of materials with spatial gradients in grain size, typically from the surface to the bulk. Here the gradient mechanical behavior inGNG copper is studied by a crystal plasticity finite elementmodel that accounts for grainsize-dependent yield strengths. The associated finite element simulations reveal both the gradient stress and gradient plas...

Full surface strain measurement requires the determination of two out-of-plane and four in-plane displacement gradient components of the surface strain tensor. Shearography is a full-field speckle interferometry technique with a sensitivity predominately to the out-of-plane displacement gradient. Speckle pattern photography has the sensitivity to the in-plane displacement, and taking the deriva...