Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

In this paper, micromechanics methods are applied to characterize the damage of plate structures, both Love-Kirchhoff and Reissner-Mindlin plates, due to microcrack distribution. Analytical expressions for effective stiffness of a damaged plate with distributed microcracks are derived for the first time. The results are compared with the results based on continuum damage theory, and it is found...

OVERVIEW OF INTEGRATION METHODS FOR ELASTOPLASTICITY Constitutive relations for elastoplasticity are generally expressed in incremental form, as described in an earlier chapter. The relation between incremental stress and incremental strain may be expressed in a general incremental form that incorporates the properties of elasticity, strain additivity, and plastic flow rule. For strain-controll...