نتایج جستجو برای: structural versus non
تعداد نتایج: 1930725 فیلتر نتایج به سال:
BACKGROUND MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo. METHODS Using in silico analysis, miRNAs predicted to target the 3'untranslated region (3'UTR) of the human ATF6 mRNA...
Several structural brain abnormalities have been associated with aggression in patients with schizophrenia. However, little is known about shared and distinct abnormalities underlying aggression in these subjects and non-psychotic violent individuals. We applied a region-of-interest volumetric analysis of the amygdala, hippocampus, and thalamus bilaterally, as well as whole brain and ventricula...
Misclassification of disease status and risk factors is one of the main sources of error in studies. Wrong assignment of individuals into exposed and non-exposed groups may seriously distort the results in case-control studies. This study investigates the effect of misclassification error on odds ratio estimates and attempts to introduce a correction method. Data on 3332 men aged 30-69 years fr...
Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiovascular disorder and characterized by left ventricular hypertrophy (LVH), which unexplained abnormal loading conditions. HCM inherited as an autosomal dominant trait and, in about 40% of patients, causal mutation identified genes encoding sarcomere proteins. According to results genetic screening, patients are currently categ...
This review deals with studies that have used cDNA microarrays and immunohistochemistry to identify a subtype of breast carcinoma recently known as “basal-like” carcinoma. The key breast carcinoma studies are critically discussed to highlight methodological problems in cohort selection, definitions, interpretation of results, an...
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