نتایج جستجو برای: subacute toxicity test

تعداد نتایج: 930958  

Journal: :Tropical Journal of Natural Product Research 2023

Pavetta crassipes is a plant with many ethnomedicinal uses but has limited published data on its safety. The aim of the study was to evaluate subacute oral toxicity aqueous leaf extract P. in Wister rats. Thirty-six male rats were randomly divided into 6 groups six each. They treated with; 1 mL/kg distilled water (negative control group), (125, 250 and 500 mg/kg test respectively), 10 furosemid...

2011
Julio J. Secades

Introduction S1 Pharmacological actions S2 Traumatic lesions and experimental cerebral oedema S2 Cerebral hypoxia and ischaemia S5 Synaptic transmission and neurotransmitter levels S13 Learning performance, memory and brain ageing S17 Experimental withdrawal syndrome and intoxications S19 Toxicity S20 Acute toxicity S20 Subacute toxicity S20 Chronic toxicity S20 Teratogenicity S20 Pharmacokinet...

Journal: :International journal of clinical and experimental pathology 2014
Jiao Xu Zhi-Qiang Hu Chuan Wang Zhong-Qiong Yin Qin Wei Li-Jun Zhou Li Li Yong-Hua Du Ren-Yong Jia Mei Li Qiao-Jia Fan Xiao-Xia Liang Chang-Liang He Li-Zi Yin

The effects of acute and subacute toxicity of 1,8-cineole in Kunming mice were studied. After acute oral administration, the LD50 value (95% CL) was 3849 mg/kg (3488.8~4247.1 mg/kg). In the subacute toxicity study, there were no significant differences in body weight and relative organ weight between the control group and 1,8-cineole treatment groups. The histopathological examinations showed t...

Journal: :Biological & pharmaceutical bulletin 2014
Jin-Bin Yuan Qun Huang Gang Ren Min Shi Lai Chen Wu-Liang Yang Hai-Fang Chen Ming Yang Biao Yang Gai-Hong Yang Xiao-Quan Luo

Aristolochiae Fructus (AF) and honey-fried Aristolochiae Fructus (HAF) have been used in China for thousands of years as an anti-tussive and expectorant drug. Few clinical cases were reported associated with the toxicity of AF and HAF, although relatively high contents of aristolochic acids (AAs) were found in them. This work was designed to compare the acute and subacute toxicity of AF and HAF...

Journal: :Journal of Drug Delivery and Therapeutics 2022

Background: Despite the various medicinal applications of Glyphaea brevis, no toxicology data are available that could guarantee its safety or describe possible toxic effects. We studied acute and subacute toxicity leaf aqueous extract G. brevis (GbAE) in animal models.
 Materials methods: In study, mice were given a single oral administration GbAE at doses 1000, 2000 5000 mg/kg body weigh...

Journal: :ScienceRise 2022

The achievements of modern domestic pharmacy clearly prove the prospects searching for biologically active molecules among 1,2,4-triazole derivatives.
 aim our work was to predict safest compound, select it and unambiguously structure a new promising molecule, investigate some parameters its toxicity.
 Materials methods. X-ray diffraction analysis performed in laboratory Institute Sin...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید