purpose: to report an unusual ocular presentation of a relapse of acute lymphoblastic leukemia. case report: a 9-year-old girl presented with a subconjunctival mass and ipsilateral preauricular lymphadenopathy. she had history of acute lymphoblastic leukemia (all) in remission but had a normal blood cell profile. because of corneal dellen formation and enlargement of the mass over a 2-week peri...

Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival injection, or semiweekly 10 mcg subconjunctival injections for 3 weeks. At 1 or 3...

PURPOSE To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP). METHODS This was a prospective and nonrandomized study. A total of 291 eyes with macular edema or active choroidal neovascularization were submitted to a single 1.25 mg (0.05 mL) bevacizumab intravitreal injection. Intraocular pressure was measured with an Icare(®) tonometer imm...

PURPOSE To evaluate the tear film characteristics of spontaneous subconjunctival hemorrhage patients by Schirmer test I and tear interferometry. METHODS Forty-six spontaneous subconjunctival hemorrhage patients and 46 controls were enrolled in the study. Schirmer test I and tear interferometry were performed in all 92 subjects. The results obtained were compared between the two groups. RESU...

A 55 year old female presented with fever, skin rash and subconjunctival hemorrhage. She also developed hepatitis. Fever and skin rash lasted for more than three weeks. This patient was diagnosed to have rubella, highlighting the fact that rubella can present with atypical features like prolonged fever and rash, subconjunctival hemorrhage and hepatitis, especially in adults.

Objective- To compare the effects of topical eye-drop and subconjunctival administration of diclofenac on improvement of experimental corneal alkali wound in rabbits eyes. Design- Experimental study. Animal- fifteen rabbits. Procedures- Alkali wounds were inflicted on the central corneas of 15 rabbits which we...

  Chloroma or granulocytic sarcoma (GS) is a malignant neoplasm of myeloid lineage that occur in a variety of anatomic sites other than the bone marrow including soft tissue, bone, lymph node, nasal fossa, skin and sometime in the orbit. In the subconjunctiva it is rarely reported. A 4-year-old girl with a history of treated acute myelogenous leukemia was referred to Farabi Eye Hospital, Tehra...

The wound healing process is major cause of glaucoma surgery failure and enhances the incapability controlling IOP. This aim study was to evaluate angiogenesis effect Bevacizumab injection on amount density blood vessels in rabbit model after trabeculectomy. It a true experimental using 16 eyes New Zealand White Rabbit (Oryctolagus cuniculus) that divided into two groups. control group treated ...