BACKGROUND In mammals the interplay between the peripheral nervous system (PNS) and adipose tissue is widely unexplored. We have employed mice, which develop an adult onset of obesity due to the lack the neuronal specific transcription factor Nscl-2 to investigate the interplay between the nervous system and white adipose tissue (WAT). METHODOLOGY Changes in the architecture and innervation o...

Leptin has been shown to reduce body fat in vivo. Adipocytes express the leptin receptor, so it is realistic to expect a direct effect of leptin on adipocyte growth and metabolism. However, in vitro studies examining the effect of leptin on adipocyte metabolism require supraphysiologic doses of the protein to see a decrease in lipogenesis or stimulation of lipolysis, implying an indirect action...

Leptin has been shown to reduce body fat in vivo. Adipocytes express the leptin receptor; therefore, it is realistic to expect a direct effect of leptin on adipocyte growth and metabolism. In vitro studies examining the effect of leptin on adipocyte metabolism require supraphysiological doses of the protein to see a decrease in lipogenesis or stimulation of lipolysis, implying an indirect actio...

background: the significant increase in the number of human subcutaneous dirofilariasis in recent years, suggests the appear­ance of a new health problem in the old world with most cases reported from mediterranean countries. besides the pre­sent case, eleven cases of human subcutaneous dirofilariasis have been detected in iran, three of which belong to gilan prov­ince, northern iran. methods: ...

BACKGROUND As an important factor affecting meat quality, intramuscular fat (IMF) content is a topic of worldwide concern. Emerging evidences indicate that microRNAs play important roles in adipocyte differentiation. However, miRNAome has neither been studied during porcine intramuscular preadipocyte differentiation, nor compared with subcutaneous preadipocytes. The objectives of this study wer...

The objective of these experiments was to develop an in vitro cell culture system for differentiation of bovine preadipocytes, which will permit examination of differences in differentiation between intramuscular (i.m.) and subcutaneous (s.c.) bovine preadipocytes. Stromal-vascular cells from bovine i.m. and s.c. adipose depots were isolated and cultured. Clonally derived s.c. preadipocytes wer...