1. The metabolism of sulphanilamide, sulphadimidine (4,6-dimethyl-2-sulphanilamidopyrimidine), sulphamethoxazole (5-methyl-3-sulphanilamidoisoxazole) and sulphadoxine (5,6-dimethoxy-4-sulphanilamidopyrimidine) given by intravenous injection has been examined in cows. 2. The sulphonamides were present mainly as unchanged drugs in blood samples collected 2h after administration. 3. The sulphonami...

6. Urinary tract infections.?In acute cystitis and pyelitis and in chronic infection due to coli bacilli sulphanilamide is adequate but sulphacetamide has been particularly recommended because of its high solubility in urine. Its sodium salt (albucid soluble) may be injected intravenously in 30 per cent solution. Sulphathiazole or sulphadiazine may be given in resistant cases. The average daily...

Background: Shiga toxin-producing Escherichia coli (STEC) strains are considered to be most common food-borne enteric zoonotic pathogen, causing various disease conditions in both animals and humans highly pathogenic human low infectious doses. Resistance against antibiotics by STEC is also a big concern now days. Hence view of the public health significance STEC, present work was planned know ...

An uncontrolled used of antibiotics and sulphonamides is responsible for the presence of residues in beehive products and contributes to the problem of food safety. The optimisation of analytical methods for the detection of residues of antibacterial drugs (sulphonamides, SPs; tylosin, TL; streptomycin, ST) in honey was pursued and the methods applied to routine samples. ST was investigated by ...

in the local F. R. E. Hospital. The first three cases were treated with sulphonamides and parenteral liver extract as described in a previous publication (Sen Gupta, 1944) and as in the other cases of smallpox, and all of them died. In the course of treatment of these three patients, it appeared that these patients could not be given adequate amounts of alkalies and fluids by the mouth on accou...