Spinal muscular atrophy (SMA) is a autosomal recessive disease characterized by weakness, hypotonia and atrophy. SMA caused mutation or deletion of the survivor motor neuron gene (SMN1), which located in telomere region chromosome 5q13. Incidence 1:6000-10000 newborn. Confirmatory diagnosis can be established molecular genetic analysis. Here 2- month- old female baby was admitted into departmen...

OBJECTIVE To characterize clinical features of avian vacuolar myelinopathy (AVM) in American coots. DESIGN Case-control study. ANIMALS 26 AVM-affected American coots and 12 unaffected coots. PROCEDURES Complete physical, neurologic, hematologic, and plasma biochemical evaluations were performed. Affected coots received supportive care. All coots died or were euthanatized, and AVM status w...

Brain stem glioma is one of the diseases CNS. It brain and spinal cord tumor. a type tumor caused when healthy cells in change increase abnormally forms mass that called as This may be malignant. grows spread other parts body. Glioma tumor, it from glial cell supportive brain. A 13 year old male patient presented neurology ward with chief complaint difficulty chewing swallowing food, drooping f...

Keywords Disease name and synonyms Diagnostic criteria/definition Differential diagnosis Etiology Clinical description Diagnostic methods Genetic counseling Prenatal diagnosis Management Unresolved questions References Abstract The syndrome of Neuropathy, Ataxia, and Retinitis Pigmentosa (NARP) is clinically heterogeneous but it is often characterized by a combination of sensory-motor neuropath...

BACKGROUND Mesenteric panniculitis is a rare chronic fibrosing inflammatory disease that typically affects the adipose tissue and mesentery of the small intestine but may also affect the mesosigmoid and the mesocolon. The pathology of this disease remains unclear despite association with some malignancies or inflammatory disorders. We report a case of mesocolic panniculitis and a literature rev...

(1000mgat days0 and 14). She continued to experienceworseninglowerextremityweakness.Eventually,shereceived6plasmapheresis treatments withminimal improvement. During the entire periodof follow-up at our center, she required 20 to 30mg daily of oral prednisone. Neurological examination prior to the onset of HiCy therapy revealed symmetrically reduced arm abduction (4−/5) and hip flexion strength ...

OBJECTIVE To evaluate the incidence, clinical features, diagnostic, and treatment trends of pediatric myasthenia in Canada. METHODS Through established Canadian Pediatric Surveillance Program methodology, physicians were anonymously surveyed for cases of pediatric myasthenia using a standardized clinical questionnaire containing deidentified data. Inclusion criteria were any child <18 years o...

This article examines the evaluative nature of the folk concepts of weakness and strength of will and hypothesizes that their evaluative nature is strongly connected to the folk concepts of blame and credit. We probed how people apply the concepts of weakness and strength of will to prototypical and non-prototypical scenarios. While regarding prototypical scenarios the great majority applied th...

Acute-onset alcohol-associated neuropathy is only occasionally reported, and delayed postanoxic encephalopathy is rare. Here, we report a male who developed acute multiple focal neuropathies and later delayed postanoxic encephalopathy after alcohol intoxication. He had hypoxia and rhabdomyolysis, presenting with acute renal failure initially, and cardiopulmonary support, including mechanical ve...