نتایج جستجو برای: surface cytotoxicity

تعداد نتایج: 676964  

This study aims to characterize and evaluate the applicability of Polyhedral OligomericSilsesquioxane (POSS)/ Poly (carbonate-urea) Urethane (PCU) nanocomposite films as a temporary skin substitute by means of FTIR, MTT assay, cell proliferation assay and SEM studies. FTIR spectra showed all the characteristic peaks of POSS/PCU nanocomposite. The indirect cytotoxicity of membranes was investig...

Introduction: In the present study, various formulations of cationic liposomes were designed and prepared using different cationic lipids. It was performed to assess the physicochemical properties, miRNA loading ability and cellular toxicity rates of liposomes in order to use in gene therapy. Methods: Different cationic liposome formulations (F1-F4) containing various cationic lipids, DOTAP, D...

Journal: :Applied sciences 2023

Cobalt–chromium (CoCr) alloy is widely used for medical implants such as dental or joint replacements because of its strength and high corrosion resistance. By throwing a spherical media against material surface, fine-particle shot peening can modify surface properties and, result, has been low-cost simple method to increase metal’s wear However, no recent literature reported the effect particl...

2016
Wei Ji Diqi Zhu Yiwei Chen Jingjing Hu Fen Li

Objective: The present report describes the green synthesis of Zinc oxide nanoparticles (ZnO NPs) using Argemone maxicana leaf extract by an eco-friendly approach. Also, the in-vitro cytotoxicity of prepared ZnO NPs against the cardiac cell lines of Sahul India Catla catla fish (SICH) was studied. Methods: ZnO NPs were prepared by using Argemone maxicana leaf extract as reducing and stabilizing...

2012
Sandhya Vardharajula Sk Z Ali Pooja M Tiwari Erdal Eroğlu Komal Vig Vida A Dennis Shree R Singh

Carbon nanotubes (CNTs) are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs ...

Journal: :Nano letters 2004
Austin M Derfus Warren C W Chan Sangeeta N Bhatia

With their bright, photostable fluorescence, semiconductor quantum dots show promise as alternatives to organic dyes for biological labeling. Questions about their potential cytotoxicity, however, remain unanswered. While cytotoxicity of bulk cadmium selenide (CdSe) is well documented, a number of groups have suggested that CdSe QDs are cytocompatible, at least with some immortalized cell lines...

2010
Amudhan Maniar Xiaoyu Zhang Wei Lin Brian R. Gastman C. David Pauza Scott E. Strome Andrei I. Chapoval Andrei Chapoval

Natural killer (NK) cells are innate effector lymphocytes that control the growth of major histocompatibility complex class I negative tumors. We show here that T lymphocytes, expanded in vitro in the presence isopentenylpyrophosphate (IPP), induce NK cell–mediated killing of tumors that are usually resistant to NK cytolysis. The induction of cytotoxicity toward these resistant tumors requires ...

Journal: :International Journal of Pharmaceutics 2021

This study aims to design and characterize the layer-by-layer assembly of core-corona nanoarchitecture for novel surface-modified solid lipid nanoparticles. Oppositely charged ?-cyclodextrin polymers were used build corona structure onto core, particle size, polydispersity index, zeta potential SLN with polymer layers evaluated. Morphology was identified using TEM. The effect coating on drug re...

Journal: :Molecular cancer therapeutics 2010
Karim El-Sahwi Stefania Bellone Emiliano Cocco Francesca Casagrande Marta Bellone Maysa Abu-Khalaf Natalia Buza Fattaneh A Tavassoli Pei Hui Dominik Rüttinger Dan-Arin Silasi Masoud Azodi Peter E Schwartz Thomas J Rutherford Sergio Pecorelli Alessandro D Santin

We evaluated the expression of epithelial cell adhesion molecule (EpCAM) and the potential of MT201 (adecatumumab), a human monoclonal antibody against EpCAM, in uterine serous papillary carcinoma (USPC). EpCAM expression was evaluated by real-time PCR and immunohistochemistry in a total of 56 USPC fresh-frozen biopsies and paraffin-embedded tissues. EpCAM surface expression was also evaluated ...

2012
Masahiko Ayaki Atsuo Iwasawa Yoshimi Niwano

PURPOSE Anti-inflammatory eyedrops are often used in the treatment of corneal epithelial disorders. In the present study, we evaluated the cytotoxicity of six anti-inflammatory eyedrops in four ocular surface cell lines. METHODS The cytotoxicity of six commercially available anti-inflammatory ophthalmic solutions (ie, diclofenac, bromfenac, pranoprofen, betamethasone, and fluoromethorone) was...

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