Abstract Photopolymerization of hydrogels films has gained interest in many biomedical and industrial fields. Hydrogel micro-patterns fabricated directly on a device are used as filtering barriers, however, due to weak mechanical properties, these parts require stable support but deposition hydrogel non-polymerized state brings risk sinking inside the structure. These limitations can be overcom...

in the present investigation surface modification of silica nanoparticles by alumina was carried out by sol-gel process. fourier transform infrared (ftir) and x-ray fluorescence (xrf) confirmed the synthesis of silica and the surface modification as alumina is anchored to silica surface. field emission scanning electron microscopy (fesem) and transmission electron microscopy (tem) investigation...

We use both combinatorial and site-directed mutagenesis to explore the consequences of surface hydrophobic substitutions for the folding of two small single domain proteins, the src SH3 domain, and the IgG binding domain of Peptostreptococcal protein L. We find that in almost every case, destabilizing surface hydrophobic substitutions have much larger effects on the rate of unfolding than on th...

The interaction of membranes with peptides and proteins is largely determined by their amphiphilic character. Hydrophobic moments of helical segments are commonly derived from their two-dimensional helical wheel projections, and the same is true for β-sheets. However, to the best of our knowledge, there exists no method to describe structures in three dimensions or molecules with irregular shap...

We report successful non-adherent spheroid culture of cancer cells on hydrophobic surfaces, formed in polydimethylsiloxane (PDMS), and its extension to high-throughput culture within an integrated microfluidic device. The surface hydrophobicity was characterized by observing the contact angle of deionized water droplets. Various cell types were grown on the hydrophobic designs (circular, triang...

We propose and demonstrate hydrophobic photonic crystal fibers (PCFs). A chemical surface treatment for making PCFs hydrophobic is introduced. This repels water from the holes of PCFs, so that their optical properties remain unchanged even when they are immersed in water. The combination of a hollow core and a water-repellent inner surface of the hydrophobic PCF provides an ultracompact dissolv...