The aim of this review is to summarize the state-of the-art methods that are used in clinical organ transplantation today, as well as the major findings of recent experimental uterus transplantation (UTx) research regarding organ donation/retrieval, ischemic preservation, surgical techniques for anastomosis, immunosuppression and pregnancy. Absolute uterine factor infertility lacks treatment de...

Prenatal maternal infection is an environmental risk factor for neurodevelopmental psychiatric illness and disease-associated cognitive impairments. Modeling this epidemiological link in animals shows that prenatal immune challenge is capable of inducing long-lasting deficits in numerous cognitive domains. Here, we combined a neonatal cross-fostering design with a mouse model of prenatal immune...

Transnational surrogacy, when people travel abroad for reproduction with the help of a surrogate mother, is a heavily debated phenomenon. One of the most salient discourses on surrogacy is the one affirming that Westerners, in their quest for having a child, exploit poor women in countries such as India. As surrogacy within the Swedish health care system is not permitted, Swedish commissioning ...

in this paper, we have outlined the surrogate management framework for optimization of expensive functions. an initial simple iterative method which we call the “strawman” method illustrates how surrogates can be incorporated into optimization to stand in for the most expensive function. these ideas are made rigorous by incorporating them into the framework of pattern search methods. the smf al...

dibutyl phthalate (dbp) is a phthalic acid ester and is widely used in polymeric products to make them more flexible. dbp is found in almost every plastic material and is believed to be persistent in the environment. various analytical methods have been used to measure dbp in different matrices. considering the ubiquitous nature of dbp, the most important challenge in dbp analyses is the contam...

This short chapter introduces the SURROGATE data type, which is useful when modeling time-varying objects. Surrogates are unique identifiers that can be compared for equality, but the values of which cannot be seen by the users. In this sense, a surrogate is “pure” identity and does not describe a property (i.e., it has no observable value). For this reason, a SURROGATE data type cannot be trea...

nonlinear knapsack problems (nkp) are the alternative formulation for the multiple-choice knapsack problems. a powerful approach for solving nkp is dynamic programming which may obtain the global op-timal solution even in the case of discrete solution space for these problems. despite the power of this solu-tion approach, it computationally performs very slowly when the solution space of the pr...