Brain tissue swelling is a dangerous consequence of traumatic injury and is associated with raised intracranial pressure and restricted blood flow. We consider the mechanical effects that drive swelling of brain tissue slices in an ionic solution bath, motivated by recent experimental results that showed that the volume change of tissue slices depends on the ionic concentration of the bathing s...

From June to August 2000, we studied the effect of closed functional stabilisation treatment on the development of posttraumatic swelling. 129 patients with nondisplaced talo-crural and talo-calcanear fractures, selected for closed treatment, were randomised into three groups. The first group was treated by traditional Plaster of Paris immobilisation (PoP). In the second group the patients were...

OBJECTIVES Traumatic brain injury accounts for a high percentage of deaths in children. Raised intracranial pressure (ICP) due to brain swelling within the closed compartment of the skull leads to death or severe neurological disability if not effectively treated. We report our experience with 12 children who presented with cerebral herniation due to traumatic brain swelling in whom decompressi...

Using neutron diffraction and a specially constructed high pressure cell suitable for aligned multibilayer systems, we have studied, as a function of pressure, the much observed anomalous swelling regime in dimyristoyl- and dilauroyl-phosphatidylcholine bilayers, DMPC and DLPC, respectively. We have also reanalyzed data from a number of previously published experiments and have arrived at the f...

The subject of this study is the modeling of the evolution of the swelling pressure of granulates with cohesive-frictional, rough and elasto-plastic “microscopic” contact properties. The spherical particles are randomly arranged in a periodic cubic space with a fixed volume so that an increase of the particle size – i.e. swelling that can be caused by intake of some fluid – is accompanied by a ...

We consider a ubiquitous scenario where a fluctuating, semipermeable vesicle is embedded in solution while enclosing a fixed number of solute particles. The swelling with increasing number of particles or decreasing concentration of the outer solution exhibits a continuous phase transition from a fluctuating state to the maximum-volume configuration, whereupon appreciable pressure difference an...

Mixtures of crushed excavated COx claystone and bentonite are considered as a potential backfill solution for the French disposal concept radioactive waste. In present work, hydro-mechanical behaviour claystone/sodium mixtures was experimentally investigated various contents (≤40% in total mass) densities. Demineralized, site water cementitious alkaline were used. Test on physicochemical proper...

Submit Manuscript | http://medcraveonline.com This process may be initiated by the loss of intracellular calcium homeostasis which could activate a number of proteolytic and lipolytic systems [2]. Infiltration of mononuclear cells also occurs in the days after unaccustomed exercise. Release of secondary degradation products may increase osmotic pressures in the vicinity of the damage, and this ...

The aim of functional tissue engineering is to repair and replace tissues that have a biomechanical function, i.e., connective orthopaedic tissues. To do this, it is necessary to have accurate benchmarks for the elastic, permeability, and swelling (i.e., biphasic-swelling) properties of native tissues. However, in the case of the intervertebral disc, the biphasic-swelling properties of individu...

Tissue behavior is governed to a large extent by composition and microstructure of the extracellular matrix. In cartilage, various biopolymers (glycosaminoglycans, collagen, hyaluronic acid, etc.) are integrated into a complex network that imparts the tissue with its low-friction characteristics and load-bearing capacity. The structure of collagen (predominantly type II collagen) gives it tensi...