The involvement of Ca(2+)-storage organelles in the modulation of synaptic transmission is well-established [M.K. Bennett, Ca(2+) and the regulation of neurotransmitter secretion, Curr. Opin. Neurobiol. 7 (1997) 316-322 [1]; M.J. Berridge, Neuronal calcium signaling, Neuron 21 (1998) 13-26 [2]; Ph. Fossier, L. Tauc, G. Baux, Calcium transients and neurotransmitter release at an identified synap...

Synaptic Transistors In article number 2200733, Ye Zhou and co-workers design a multi-terminal MoS2 synaptic transistor to mimic the parallel signal transmission behaviors of biological multipolar neurons. With combination microstructured pressure sensors, an intelligent tactile recognition system is built up realize spatiotemporal modulation plasticity.

This study was conducted to clarify the electrical and spectral properties of the combined photoresponses of two extra-ocular photoreceptor neurones, A-P-l and Es-1, in the abdominal ganglion of the marine mollusc Onchidium verruculatum. The depolarizing receptor potential or inward receptor current of Es-1 appeared to result from a decrease in K conductance, in the same way as in A-P-l. The di...

BACKGROUND An increasing number of studies report associations between variation in DTNBP1, a top candidate gene in schizophrenia, and both the clinical symptoms of the disorder and its cognitive deficits. DTNBP1 encodes dysbindin-1, reduced levels of which have been found in synaptic fields of schizophrenia cases. This study determined whether such synaptic reductions are isoform-specific. M...

Serotoninergic Retzius neurons reform an inhibitory synapse onto pressure-sensitive mechanosensory (P) neurons when the cells are removed from the nervous system of the leech and are juxtaposed in tissue culture. The somas of P cells in situ and single (uninnervated) P cells in culture have both a depolarizing and Cl-dependent hyperpolarizing response to application of the transmitter serotonin...

Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...