نتایج جستجو برای: systemic inflammation

تعداد نتایج: 329587  

Journal: :Arthritis Research & Therapy 2007
Loic Guillevin Thomas Dörner

Systemic vasculitis, an inflammatory necrotizing disease of the blood vessel walls, can occur secondary to autoimmune diseases, including connective tissue diseases. Various pathogenic mechanisms have been implicated in the induction of vasculitis, including cell-mediated inflammation, immune complex-mediated inflammation and autoantibody-mediated inflammation. This inflammatory activity is bel...

2015
Loic Guillevin Thomas Dörner

Systemic vasculitis, an inflammatory necrotizing disease of the blood vessel walls, can occur secondary to autoimmune diseases, including connective tissue diseases. Various pathogenic mechanisms have been implicated in the induction of vasculitis, including cell-mediated inflammation, immune complex-mediated inflammation and autoantibody-mediated inflammation. This inflammatory activity is bel...

2013
Marco Busnelli Stefano Manzini Alberto Froio Alessia Vargiolu Maria Grazia Cerrito Ryszard T. Smolenski Massimo Giunti Alessandro Cinti Augusta Zannoni Biagio Eugenio Leone Monica Forni Maria Laura Bacci Giorgio Maria Biasi Roberto Giovannoni Marialuisa Lavitrano

OBJECTIVE The aim of the present study was to comprehensively evaluate systemic and local inflammation as well as progression of vascular inflammation in normal and mechanically injured vessels in a large animal model of mild hypercholesterolemia. Our aim was also to test the effect of high-dose statin treatment on these processes. METHODS Pigs were kept for 120 days on a standard diet (SD, n...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
Barry W McColl Nancy J Rothwell Stuart M Allan

Systemic inflammatory events, such as infection, increase the risk of stroke and are associated with worse outcome, but the mediators of this clinically important effect are unknown. Our aim here was to elucidate mechanisms contributing to the detrimental effects of systemic inflammation on mild ischemic brain injury in mice. Systemic inflammation was induced in mice by peripheral interleukin-1...

2008
Barry W. McColl Nancy J. Rothwell Stuart M. Allan

Systemic inflammatory events, such as infection, increase the risk of stroke and are associated with worse outcome, but the mediators of this clinically important effect are unknown. Our aim here was to elucidate mechanisms contributing to the detrimental effects of systemic inflammation on mild ischemic brain injury in mice. Systemic inflammation was induced in mice by peripheral interleukin-1...

Journal: :Journal of the American College of Cardiology 2019

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