MicroRNAs (miRNAs, miRs) are small endogenous non-coding RNAs that regulate the expression of protein-encoding genes at the post-transcriptional level. Several studies have described the role of miRNAs in T-cell acute lymphoblastic leukemia (T-ALL), including tumor suppressor and oncogenic miRNAs. Down-regulation of miRNA expression is a prominent feature of human malignancy. This down-regulati...

Abstract Introduction/Objective N/A. Methods/Case Report Acute leukemias with ambiguous lineage encompass those that show no clear evidence of differentiation along a single and account for less than 4% all cases acute often poses diagnostic dilemma. We present challenging case an leukemia in previously healthy 27-year-old male, who presented to the ED fever, dyspnea on exertion, nausea vomitin...

introduction: oral candidosis is among the find-ings of acute leukemia. the aim of this study was to evaluate the changes in the intensity of c.albicans, before treatment and at the induc-tion phase. materials and methods: twelve patients with acute lymphoblastic leukemia (all) aged 2-14 years enrolled in study. whole saliva samples were obtained and cultured to determine the mean count of c.al...