Nine polymorphic microsatellite loci were isolated and characterized in Taxus wallichiana var. wallichiana, an endangered species in China. The number of alleles per locus ranged from 2 to 20. Observed and expected heterozygosities varied from 0.0260 to 0.5325 and 0.3603 to 0.9231, respectively. Positive cross-amplification of the 9 loci was observed in 2 other varieties of T. wallichiana and 4...

taxol is used to treatment of variety cancers including ovarian, breast, lung, head and neck carcinomas and the aids-related karposi’s carcinoma, and was originally obtained from bark of taxus brevifolia. however the amount of extracted taxol from taxus is extremely low and cannot be considered as a suitable commercial source and it has led to studies for finding new sources of taxol. in 1998, ...

Endophytic bacteria have been extensively studied as a source of new antimicrobial compounds. Research into antimicrobials is important an alternative to the treatment resistant microbes. One potential compounds Taxus ( sumatrana ). This study aimed investigate activity produced by endophytic Taxus. were isolated from roots Taxsus plants growing in Mt. Singalang, X Koto District, West Sumatra. ...

The applicability of a new mass spectrometric technique, DART (direct analysis in real time) has been studied in the analysis of the calli of Taxus wallichiana. The intact callus samples were directly analyzed by holding them in the gap between the DART source and mass spectrometer for measurements. Five C-14 oxygenated taxoids were characterized from the analysis of the calli of the Taxus wall...

Twenty-eight leaf and twig samples and one bark sample of Taxus baccata from the Ukraine (Crimea), Russia, and Georgia were analyzed for taxane compounds. Taxol and the related diterpenoid I 0-deacetylbaccatin III (baccatin Ill) were present in all samples and 20.7% of those samples exhibited a taxol content nearly equal to or greater than that obtained from the bark of the Pacific Yew, T. brev...

Flavanols and flavonols of mitotic and post-mitotic nuclei in needles of Taxus baccata L., Tsuga canadensis L., and slow growing dwarf genotypes of both genera are investigated histochemically. The flavanols of nuclear chromatins and in the vacuoles stain blue with the p-dimethylamino-cinnamaldehyde (DMACA) reagent. Flavonols do not react with the reagent but owing to their UV absorbance they c...

BACKGROUND Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. The phytohormone methyl jasmonate (MeJA) can significantly increase the production of paclitaxel, which is induced in plants as a secondary metabolite possibly in defense ag...

Background—The safety and efficacy of the slow-release, polymer-based, paclitaxel-eluting stent after implantation in a broad cross section of de novo coronary lesions at 1 year are unknown. Methods and Results—In the TAXUS-IV trial, 1314 patients with single de novo coronary lesions 10 to 28 mm in length, with reference-vessel diameter 2.5 to 3.75 mm, coverable by a single study stent, were pr...

have a negligible impact on the analysis. Our findings of a more pronounced antirestenotic effect (P, 0.001) in Cypher vs. Taxus have actually raised concerns that most of the relative risk reduction apparent with Cypher was due to the severely inferior performance of Bx Velocity (a well-known thick strut BMS) when compared with the substantially superior performance of Cypher [when compared wi...