OBJECTIVES The purpose of this study was to determine how frequently and for what reasons the addition of electrocardiographically gated technetium-99m (Tc-99m) sestamibi single-photon emission computed tomographic (SPECT) images add value to nongated SPECT perfusion images. BACKGROUND Electrocardiographic gating of Tc-99m sestamibi SPECT images permits assessment of regional and global left ...

introduction: we aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected cad is different from that of intravenous (iv) dipyridamole using tc-99m mibi myocardial perfusion gated spect. methods: eighty-nine patients (17 m / 72 w; 61 ± 10 years) were enrolled in this study. the patients underwent a dipyridamole stres...

Scintimammography performed with Tc-99m sestamibi in a 63-year-old woman with a history of mitral valve replacement and pulmonary hypertension demonstrated that the frequently observed sternal hyperactivity on anterior views could arise from the myocardium. Caution therefore should be taken before the diagnosing hyperactivity in the lower sternal region as a neoplastic involvement. Fig. 1. Scin...

We report the case of a 71-year-old woman who was referred to our institute with a solid nodule in the right thyroid lobe and hypercalcemia. Ultrasound revealed a well-vascularized right thyroid nodule that was identified as a cold area by (99m)Tc-sodium pertechnetate scan. Fine-needle aspiration showed a follicular lesion and blood tests revealed hypercalcemia and hyperparathyroidism. A (99m)T...

UNLABELLED This study was done to examine the effect of asiaticoside on MCF-7 cell uptake of (99m)Tc-tetrofosmin ((99m)Tc-Tfos) and (99m)Tc-sestamibi ((99m)Tc-MIBI). METHODS The 3-(4,5-dimethylthiozol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to evaluate the effect of a 50% inhibitory concentration of asiaticoside on MCF-7 cell proliferation. MCF-7 cells were treated with 10,...

Previous reports have shown that (99m)Tc-sestamibi (MIBI) could detect clinically occult metastatic melanoma lesions. This article reports on a patient with invasive melanoma of the right heel in whom the sentinel node status was preoperatively evaluated with this tracer. Although regional lymph nodes were clinically negative, (99m)Tc-MIBI scintigraphy showed focal increased tracer uptake in th...

A case of follicular thyroid cancer with intense focal Methionine uptake on 11C-Methionine PET/CT is reported here. The use of 11C-Methionine PET in differentiated thyroid cancer is currently being investigated as a surrogate tracer compared to the more widely used 18F-FDG PET. This case illustrates the potential incremental value of this modality, not only in the localizing of parathyroid aden...