BACKGROUND Due to limitations of the Friedewald formula, alternative methods for calculating low-density lipoprotein cholesterol (LDL-C) were suggested. We evaluated utility of these methods. METHODS Ninety three subjects free of coronary heart disease were considered. LDL-C was measured by the homogeneous method, and calculated by the Friedewald formula LDL-C = TC-HDL-(TG/2.2) (LDL1) and alt...

BACKGROUND The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults. METHODS Randomized controlled trials that examined the effects of walking on total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), the ratio of TC/HDL, and triglycerides (TG) in adults ages 18 years and older were...

AIM The combination of ezetimibe and a statin provides greater LDL-C reduction by inhibiting both intestinal cholesterol absorption and endogenous production of cholesterol. The present study was designed to examine the influence of ageing, gender, BMI, levels of LDL-C, and HbA1c on the response to ezetimibe add-on therapy. METHODS Patients who had been taking a statin for >3 months at the us...

BACKGROUND Information about the interactions of single nucleotide polymorphisms (SNPs) and overweight/obesity on serum lipid profiles is still scarce. The present study was undertaken to detect ten SNPs and their interactions with overweight/obesity on serum lipid levels. METHODS A total of 978 normal weight and 751 overweight/obese subjects of Bai Ku Yao were randomly selected from our prev...

BACKGROUND Animal studies have demonstrated that an inhibition of DPP-4 has an impact on the secretion of cholesterol and apoB by the small intestine. However, there is no consensus about the changes of the lipid profile following administration of sitagliptin. METHODS Accordingly, we treated patients who had type 2 diabetes complicated by dyslipidemia with sitagliptin and evaluated its effec...

Background and Objectives: Dyslipidemia is a family of lipoprotein metabolism disorders manifested by elevated total cholesterol (TC), low-density (LDL-C), triglycerides (TG), reduced high density (HDL-C) concentrations in the blood.[1] was defined according to criteria National Cholesterol Education Program Adult Treatment Panel III. Hypercholesterolemia declared for participants with either ˃...

A female patient (64 years of age; body mass index, 26) had a markedly and relatively low low-density lipoprotein-cholesterol (LDL-C) level (97 mg/dl) despite high serum total cholesterol (TC) (331 mg/dl) and triacylglyceride levels (307 mg/dl). Since the expected LDL-C was 222 mg/dl, there was a significant difference between the calculation and measurement based on direct enzyme assay. Only 3...

Introduction: The present study aimed to evaluate the effects of pectin supplementation and 14 weeks of endurance training on the serum atrial natriuretic peptide (ANP) levels and lipid profile of obese pregnant mice. Methods: This experimental study was conducted on 40 female laboratory mice (mean weight: 30+5 g...

Ischaemic Cerebrovascular Accident (CVA) has been shown to be associated with abnormal lipid profile (dyslipidaemia) as a risk factor. There is paucity of data regarding this in this environment hence this study. In this study, a total number of 63 subjects were recruited comprised of 33 patients with cerebrovascular accident (stroke) and 30 apparently healthy volunteers as control. A complete ...