UNLABELLED This study on a rat model of grade II chondrosarcoma aimed to determine whether the radiotracer N-(triethylammonium)-3-propyl-[15]ane-N5 radiolabeled with (99m)Tc ((99m)Tc-NTP 15-5), which binds to cartilage proteoglycans, has pathophysiologic validity for in vivo imaging of cartilage tumoral tissue. METHODS We used 2 experimental approaches with the Swarm chondrosarcoma rat model:...

Using the stack-foil activation technique, excitation functions were measured for (p, x) reactions on Monat target. The target was irradiated with a proton beam of 17 MeV kinetic energy. Along medically important radioisotopes Mo99/Tc99m we studied other long-lived radio-impurities produced in Cross sections all from Monat(p,x) are compared available literature data, which show good agreement.

we report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. a 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with tc-99m hydroxymethylene diphosphonate (hmdp) and single-photon emission computed tomography/computed tomography (spect/ct). the lesion was rich in blood flow acc...

Rhemium-186-1-hydroxyethylidene-1,1-diphosphonate ((186)Re-HEDP) has been used for the palliation of metastatic bone pain. However, delayed blood clearance and high gastric uptake of radioactivity have been observed upon injection, due to the instability of (186)Re-HEDP. We designed, synthesized and evaluated a stable (186)Re-mercaptoacetylglycylglycylglycine (MAG3) complex-conjugated bisphosph...

The enantioselective fluorination of readily available cyclic allylic chlorides with AgF has been accomplished using a Pd(0) catalyst and Trost bisphosphine ligand. The reactions proceed with unprecedented ease of operation for Pd-mediated nucleophilic fluorination, allowing access to highly enantioenriched cyclic allylic fluorides that bear diverse functional groups. Evidence that supports a m...

Highly enantioselective hydrogenation of various N-Boc-indoles proceeded successfully in the presence of the ruthenium complex generated from an appropriate ruthenium precursor and a trans-chelate chiral bisphosphine PhTRAP. Various 2- or 3-substituted indoles were converted into chiral indolines with high enantiomeric excesses (up to 95% ee). The PhTRAP-ruthenium catalyst was able to promote t...

Abstract The steels with excellent strength and ductility are expected to be achieved by tailoring the microstructural features. In this work, laminate dual-phase (DP) high martensite content (laminate HMDP steels) were produced a combination of warm rolling intercritical annealing. Influence strain annealing temperature on evolution mechanical properties systematically studied. was significant...