PURPOSE To examine clinical findings and histologic changes on the conjunctival surface in ocular rosacea. METHODS Thirty-five patients with ocular rosacea and 30 normal subjects underwent dermatologic and ocular examinations. Tear film break-up time, Schirmer tests with and without topical anesthesia, and conjunctival impression cytology were done. Patients were divided into the following gr...

JANUARY 2012 CATARACT & REFRACTIVE SURGERY TODAY 19 N early one in five individuals in North America has dry eye disease (DED); it may be one of the most common yet frequently undiagnosed and untreated problems seen every day by ophthalmologists.1 Less appreciated, perhaps, are the profound visual impact of DED and the progressive nature of the disease if left undiagnosed and untreated. A hallm...

Dry eye disease is a multifactorial chronic disorder of the ocular surface that affects up to 100 million people worldwide. During the pathogenesis of dry eye, impaired function of the lacrimal and meibomian glands results in hyposecretion of aqueous tear fluid, coupled with increased evaporation and instability of the tear film, which becomes increasingly hyperosmolar in character at more seve...

Purpose To determine the effect of night-time working on dry eye signs and symptoms. Methods A total of 50 healthy subjects completed a dry eye questionnaire and underwent clinical examinations including basic Schirmer's test and tear breakup time (TBUT) test on two consecutive days, before and after the night shift (12-hrs night-shift). Results All dry eye symptoms were aggravated signific...

Extensive studies have explored the dynamics of the ocular surface fluid, though theoretical investigations are typically limited to the use of the lubrication approximation, which is not guaranteed to be uniformly valid a-priori throughout the tear meniscus. However, resolving tear film behaviour within the meniscus and especially its apices is required to characterise the flow dynamics where ...

PURPOSE The purpose of this work was to gather preliminary data in normals and dry eye subjects, using a new, non-invasive imaging platform to measure the thickness of pre-corneal tear film. METHODS Human subjects were screened for dry eye and classified as dry or normal. Tear film thickness over the inferior paracentral cornea was measured using laser illumination and a complementary metal-o...

PURPOSE To synthesize an interference color chart for the specific tear lipid layer interference camera, DR-1, for the conversion of the tear film lipid layer thickness into color graphic information--that is, for the quantification of the tear interference image--by a colorimetric approach. METHODS Because the color of the tear lipid layer interference image is visualized by a white light so...

PURPOSE We investigated the effects of a visual picking system on ocular comfort, the ocular surface and tear function compared to those of a voice guided picking solution. DESIGN Prospective, observational, cohort study. METHOD SETTING Institutional. STUDY POPULATION A total of 25 young asymptomatic volunteers performed commissioning over 10 hours on two consecutive days. MAIN OUTCO...

PURPOSE To examine tear film, contact lens, medical, and patient-related factors associated with self-reported contact lens-related dry eye. METHODS Four hundred fifteen contact lens wearers were recruited and enrolled in this phase of a larger cross-sectional study. A variety of tear film (e.g., interferometry, osmolality, phenol red thread, meibography, fluorescein, and lissamine green stai...