Background: Hyperbilirubinemia is a common problem in neonates that affects approximately 60% of term neonates and 80% of pre-term neonates in the first week of life. Newborns, due to prematurity of the liver and digestive tract, could not eliminate bilirubin quickly. This phenomenon leads to hyperbilirubinemia and jaundice during the first days of the birth. Because indirect bilirubin is toxi...

INTRODUCTION In the search for biomarkers that allow the prediction of neonatal growth and development, placental growth hormone(PGH), pituitary growth hormone (GH1), insulin-like growth factor 1 (IGF-1), and ghrelin concentrations were assessed in the amniotic fluid and in the umbilical cord blood of 92 neonates. MATERIAL AND METHODS The proteins were assayed by the ELISA method. Their conce...

Perinatal stroke in neonates can lead to disability in later life. However, its etiology and prognosis are poorly understood. The aim of this study was to describe clinical presentations and neurodevelopmental outcomes of our case series of perinatal stroke in Korea. Thirteen term and preterm neonates who were diagnosed with perinatal stroke in two university hospitals from March 2003 to March ...

OBJECTIVE Presepsin (soluble CD14 subtype) has been shown to be beneficial as a sepsis marker in adults. Nevertheless, very few data are available in neonates. The aim of the present study was to determine reference ranges of presepsin in term and preterm neonates. METHODS Healthy term neonates and preterm neonates without clinical signs of infection admitted to the Neonatal Unit were consecu...

OBJECTIVE To compare the efficacy of phenobarbitone and phenytoin for treatment of neonatal seizures in term and near-term neonates. DESIGN Open labeled randomized controlled trial. SETTING Neonatal intensive care unit of a level II unit from India, from November 2008 to September 2009. PARTICIPANTS All term and late pre-term neonates admitted with clinically apparent seizures and not hav...

Preterm birth represents a high risk of neurodevelopmental disabilities when associated with white-matter damage. Recent studies have reported cognitive deficits in children born preterm without brain injury on MRI at term-equivalent age. Understanding the microstructural and metabolic underpinnings of these deficits is essential for their early detection. Here, we used diffusion-weighted imagi...

Breast-feeding is a normal way of promoting bonding and attachment between neonates and mothers. Breast-feeding is not just as food sources, but a source of comfort and security. A study was conducted to evaluate the effectiveness of breast-feeding on procedural pain among term neonates in KKCTH, Chennai, 2008-2009. The objective of the study was to evaluate the effectiveness of Breast-feeding ...

OBJECTIVE Only a few studies on improving the early diagnosis of severe neonatal infections have focused on the role of serum RANTES concentration (sRC). The aim of the study was to establish sRC in neonates with early-onset infections, according to their gestational age, sex, birth asphyxia, mode of delivery and value of some biochemical and hematological parameters. MATERIAL/METHODS The ana...

Introduction: Evaluation of the cerebrospinal fluid (CSF) white blood cell (WBC) count and glucose and protein concentrations is used to assess the probability of the presence of central nervous system (CNS) infection. Although normal values are well established for CSF cell counts and protein and glucose contents in children and adults, this is not the case for neonates. The purpose of this st...