A key consideration of the TERRA programme, however, was that European spatial planning cannot represent the sum of the various national and/or regional and local views. It must be the result of integrating these into a joint vision of the development of the European territory, based on both major areas of agreement and on the diversities and specific characteristics of this territory (see Euro...

Neste trabalho são descritas as condições de emergência da matéria e da vida na Terra, confrontando as várias teses sobre o tema. Optando por uma via neo-darwinista como critério de compreensão da evolução das espécies, o trabalho sustenta que a eclosão da vida no nosso planeta representa o mais que provável sinal de uma propriedade intrínseca do Universo no seu todo. Ou seja, aponta para a for...

DNA:RNA hybrids, nucleic acid structures with diverse physiological functions, can disrupt genome integrity when dysregulated. Human telomeres were shown to form hybrids with the lncRNA TERRA, yet the formation and distribution of these hybrids among telomeres, their regulation and their cellular effects remain elusive. Here we predict and confirm in several human cell types that DNA:RNA hybrid...

Telomeres are protective nucleoprotein structures at the ends of eukaryotic chromosomes. Despite the heterochromatic state of telomeres they are transcribed, generating non-coding telomeric repeat-containing RNA (TERRA). Strongly induced TERRA transcription has been shown to cause telomere shortening and accelerated senescence in the absence of both telomerase and homology-directed repair (HDR)...

The algorithms for estimating snow extent for the Moderate Resolution Imaging Spectroradiometer (MODIS) optimally use the 1.6-μm channel which is unavailable for MODIS on Aqua due to detector damage. As a test bed to demonstrate that Aqua band 6 can be restored, we chose the area surrounding Yellowstone and Grand Teton national parks. In such rugged and difficult-to-access terrain, satellite im...

THE discovery of a new drug, terra Silesiaca, in the sixteenth century and the publicity and experimentation that were a part of marketing it provide an interesting insight into the medical practice and the pharmaceutical trade of that period. Various earths had long been used in medicine as alexipharmics, astringents, and absorbents. In the first century AD, Dioscorides and Pliny the Elder des...

The research vessel-based Conductivity Temperature Depth profiler (CTD) provides underwater measurements of the bulk sea surface temperature (SST) at the depths of shallower than 5 m. The CTD observations of the seas around Taiwan provide useful data for comparison with SST of MODIS (Moderate Resolution Imaging Spectroradiometers) aboard Aqua and Terra satellites archived by JAXA (Japan Aerospa...

Introduction: The martian highlands preserve a long and complex history of degradation by fluvial, eolian, and mass wasting processes [1-8]. The effects of these processes are best observed on impact craters that characterize the ancient highlands. Previous studies of highland terrains Margaritifer Sinus [9,10], Ismenius Lacus [11,12], Arabia Terra [13], and Promethei Terra [14,15] have shown t...