A capillary electrochromatography (CEC) monolithic column with zwitterionic stationary phases was prepared by in situ polymerization of butyl methacrylate, ethylene dimethacrylate, methacrylic acid, and 2-(dimethyl amino) ethyl methacrylate in the presence of porogens. The stationary phases have zwitterionic functional groups, that is, both tertiary amine and acrylic acid groups, so the ionizat...

In the title compound, C24H40N4S3 (4+)·2SiF6 (2-)·3CH3OH, the central tertiary amine function is protonated and is connected to three thio-phen-2-yl-methyl-amino-n-propyl groups, forming the arms of a T-shaped cation that has two pockets. Each arm contains one protonated secondary amine function, and each pocket is occupied by one SiF6 (2-) anion bonded via two N-H⋯F inter-actions with the prot...

A generic coarse-grained (CG) protein model is presented. The intermediate level of resolution (four beads per amino acid, implicit solvent) allows for accurate sampling of local conformations. It relies on simple interactions that emphasize structure, such as hydrogen bonds and hydrophobicity. Realistic alpha/beta content is achieved by including an effective nearest-neighbor dipolar interacti...

Knowing the tertiary structure of proteins is important to predict protein function and to achieve rational drug design. However, huge amounts of money and time are needed to determine tertiary structures by experimental method. Only a small number of protein structures have been experimentally determined; therefore, prediction of the tertiary structure of proteins by computer should be of grea...

No evidence has been found to show that the protease is a mixture ofenzymes or that the protease of one plant is distinguishable from another. It has been customary to name a protease after the generic name of the plant in which it is found. This custom, both here and in future work, implies an indefinite extension in the number of proteases. It is therefore recommended that the proteases descr...

An efficient primary-amine-directed, palladium-catalyzed C?H halogenation (X=I, Br, Cl) of phenylalanine derivatives is reported on a range quaternary amino acid (AA) thanks to suitable conditions employing trifluoroacetic as additive. The extension this original native functionality-directed ortho-selective was even demonstrated with the more challenging tertiary AA.

Helical peptides built principally from the achiral quaternary amino acid Aib but with an induced preferred screw-sense exhibit enantioselectivity in their chain-extension reactions when presented with a racemic tertiary amino acid. This is the first demonstration that secondary structure alone, in the absence of local chiral residues, can direct the enantioselectivity of peptide coupling.

functionalization of multiwalled carbon nanotubes (mwcnts) with nh2 groups under a one pot reaction is studied. during the first step of the reaction, cl and chcl2 groups were attached to the surfaces of mwcnts through an electrophilic addition reaction. in the second step of process, cl atoms were replaced with nh2 and amino groups (ethylene diamine and butyl amine) under a nucleophilic substi...

One of the trends of modern cellulose chemistry is the functionalization of known cellulose derivatives in order to expand their application area. In this work, water-soluble cationic cellulose derivatives containing up to 4% coupled nitrogen were obtained by the amination of hydroxyethylcellulose (HEC) with two different etherification agents, diethylepoxypropylamine (DEEPA) and (2-chlorethyl)...